| ID | 109480 |
| Title Alternative | LIPUSはミニスクリューインプラント周囲の骨形成を促進する
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| Author |
Ganzorig, Khaliunaa
Tokushima University
Maeda, Yuichi
Tokushima University
Mansjur, Karima
Tokushima University
Sato, Minami
Tokushima University
Nagata, Kumiko
Tokushima University
Tanaka, Eiji
Tokushima University
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| Keywords | Low-intensity pulsed ultrasound
miniscrew implant
bone formation
stainless steel and titanium
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| Content Type |
Thesis or Dissertation
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| Description | Miniscrew implants (MSIs) are currently used to provide absolute anchorage in orthodontics; however, their initial stability is an issue of concern. Application of low-intensity pulsed ultrasound (LIPUS) can promote bone healing. Therefore, LIPUS application may stimulate bone formation around MSIs and enhance their initial stability. Aim. To investigate the effect of LIPUS exposure on bone formation after implantation of titanium (Ti) and stainless steel (SS) MSIs. Methods. MSIs made of Ti-6Al-4V and 316L SS were placed on rat tibiae and treated with LIPUS. The bone morphology around MSIs was evaluated by scanning electron microscopy and threedimensional micro-computed tomography. MC3T3-E1 cells cultured on Ti and SS discs were treated with LIPUS, and the temporary expression of alkaline phosphatase (ALP) was examined. Results. Bone-implant contact increased gradually from day 3 to day 14 after MSI insertion. LIPUS application increased the cortical bone density, cortical bone thickness, and cortical bone rate after implantation of Ti and SS MSIs (P < 0.05). LIPUS exposure induced ALP upregulation in MC3T3- E1 cells at day 3 (P < 0.05). Conclusion. LIPUS enhanced bone formation around Ti and SS MSIs, enhancing the initial stability of MSIs.
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| Journal Title |
Archives of Oral Biology
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| ISSN | 00039969
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| NCID | AA00548457
AA11521918
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| Publisher | Elsevier
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| Volume | 60
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| Issue | 6
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| Start Page | 902
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| End Page | 910
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| Published Date | 2015-03-04
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| Remark | 内容要旨・審査要旨・論文本文の公開:
内容要旨 : LID201509181001.pdf 審査要旨 : LID201509181002.pdf 論文本文 : k2863_fulltext.pdf 著者の申請により要約(2015-09-18公開)に替えて論文全文を公開(2019-06-10) 本論文は, 著者Khaliunaa Ganzorigの学位論文として提出され, 学位審査・授与の対象となっている。 |
| Rights | © 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license
http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| EDB ID | |
| DOI (Published Version) | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
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| TextVersion |
ETD
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| MEXT report number | 甲第2863号
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| Diploma Number | 甲口第402号
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| Granted Date | 2015-09-16
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| Degree Name |
Doctor of Dental Science
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| Grantor |
Tokushima University
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| departments |
Oral Sciences
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