ID | 106142 |
Title Alternative | 軟部病変におけるF-18 FDG PET/CTと病理所見との相関関係
FDG-PET/CT findings of soft tissue lesoions
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Author |
Nose, Hayato
The University of Tokushima
Otsuka, Hideki
The University of Tokushima
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Otomi, Yoichi
The University of Tokushima
Tokushima University Educator and Researcher Directory
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Terazawa, Kaori
The University of Tokushima
Takao, Shoichiro
The University of Tokushima
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Harada, Masafumi
The University of Tokushima
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Keywords | F-18 FDG PET
soft tissue tumor
myxoid tumor
neurogenic tumor
liposarcoma
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Content Type |
Thesis or Dissertation
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Description | Objective : To evaluate the correlations between F-18 FDG uptake imaged with PET/CT and pathological findings in soft tissue lesions. Methods : Fifty-four soft tissue lesions in 47 patients were evaluated. The correlations between the degree of FDG uptake, pathological type and grade, and MRI signal intensity and/or enhancement pattern were evaluated. Tumor FDG uptake was quantified by the maximum standardized uptake value (SUVmax). Results : Thirty-one lesions were malignant and twenty-three lesions were benign. The difference between SUVmax in the malignant and benign groups was statistically significant (p<0.001). Malignant myxoid lesions and well differentiated liposarcoma showed low FDG uptake. Benign neurogenic lesions showed low FDG uptake while malignant neurogenic tumors showed high FDG uptake, and the difference between SUVmax in the benign and malignant lesions was statistically significant (p<0.001). In a neurofibromatosis type-1 patient who had multiple neurogenic tumors, FDG-PET/CT could distinguish malignant peripheral nerve sheath tumors from other benign lesions with similar MRI findings. Conclusions : FDG-PET/CT is useful for differentiating malignant from benign soft tissue lesions, but malignant soft tissue lesions may show various patterns on FDG-PET, and MRI may be helpful for a differential diagnosis.
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Journal Title |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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NCID | AA12022913
AA11166929
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Publisher | Tokushima University Faculty of Medicine
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Volume | 60
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Issue | 3-4
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Start Page | 184
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End Page | 190
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Sort Key | 184
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Published Date | 2013-08
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Remark | 内容要旨・審査要旨・論文本文の公開
内容要旨・審査要旨 : LID201405131013.pdf 論文本文 : k2749_fulltext.pdf 本論文は,著者Hayato Noseの学位論文として提出され,学位審査・授与の対象となっている。 著者の申請により要約(2014-05-23公開)に替えて論文全文を公開(2019-12-20) |
EDB ID | |
DOI (Published Version) | |
URL ( Publisher's Version ) | |
FullText File | |
language |
eng
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TextVersion |
ETD
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MEXT report number | 甲第2749号
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Diploma Number | 甲医第1210号
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Granted Date | 2014-03-24
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Degree Name |
Doctor of Medical Science
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Grantor |
Tokushima University
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departments |
Medical Sciences
University Hospital
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