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ID 116972
Author
Zheng, Robert Tokushima University
Okushi, Yuichiro Tokushima University
Okayama, Yoshihiro Tokushima University
Nakai, Michikazu National Cerebral and Cardiovascular Center
Sumita, Yoko National Cerebral and Cardiovascular Center
Content Type
Journal Article
Description
Background
Cardiovascular diseases are the second most common cause of mortality among cancer survivors, after death from cancer. We sought to assess the impact of cancer on the short-term outcomes of acute myocardial infarction (AMI), by analysing data obtained from a large-scale database.
Methods
This study was based on the Diagnosis Procedure Combination database in the Japanese Registry of All Cardiac and Vascular Diseases and the Diagnosis Procedure Combination. We identified patients who were hospitalised for primary AMI between April 2012 and March 2017. Propensity Score (PS) was estimated with logistic regression model, with cancer as the dependent variable and 21 clinically relevant covariates. The main outcome was in-hospital mortality.
Results
We split 1 52 208 patients into two groups with or without cancer. Patients with cancer tended to be older (cancer group 73±11 years vs non-cancer group 68±13 years) and had smaller body mass index (cancer group 22.8±3.6 vs non-cancer 23.9±4.3). More patients in the non-cancer group had hypertension or dyslipidaemia than their cancer group counterparts. The non-cancer group also had a higher rate of percutaneous coronary intervention (cancer 92.6% vs non-cancer 95.2%). Patients with cancer had a higher 30-day mortality (cancer 6.0% vs non-cancer 5.3%) and total mortality (cancer 8.1% vs non-cancer 6.1%) rate, but this was statistically insignificant after PS matching.
Conclusion
Cancer did not significantly impact short-term in-hospital mortality rates after hospitalisation for primary AMI.
Journal Title
Open Heart
ISSN
20533624
Publisher
BMJ Publishing Group|British Cardiovascular Society
Volume
8
Issue
2
Start Page
e001860
Published Date
2021-11-22
Rights
This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
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language
eng
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departments
University Hospital
Medical Sciences