| ID | 106141 |
| Title Alternative | FDG-PET/CTでの浸潤性膵管癌以外の膵腫瘍の悪性病変の検出能における視覚評価と標準摂取率での評価の比較検討
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| Author |
Otomi, Yoichi
The University of Tokushima
Tokushima University Educator and Researcher Directory
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Otsuka, Hideki
The University of Tokushima
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Terazawa, Kaori
The University of Tokushima
Nose, Hayato
The University of Tokushima
Kubo, Michiko
The University of Tokushima
Ikushima, Hitoshi
The University of Tokushima
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Bando, Yoshimi
The University of Tokushima
Tokushima University Educator and Researcher Directory
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Harada, Masafumi
The University of Tokushima
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| Keywords | FDG
PET/CT
pancreatic lesion
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| Content Type |
Thesis or Dissertation
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| Description | Introduction The utility of FDG PET/CT for the detection and evaluation of invasive ductal carcinoma has been widely reported, but a few studies have assessed the utility of FDG PET/CT to detect malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Purpose To compare the diagnostic performance of visual estimation with the semi-quantitative scores of FDG PET/CT for detecting malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Material and Methods Images of pathologically proven pancreatic lesions from 32 patients were retrospectively evaluated : 14 benign lesions, 7 borderline (low malignant) lesions, and 11 malignant lesions. The average scores from visual estimation by the two observers were compared to two semi-quantiative analyses of FDG uptake in the lesions, namely the maximum standardized uptake value (SUVmax) and mean standardized uptake value (SUVmean). Results Visual analysis value, SUVmax and SUVmean were 0.33±0.21, 1.8±0.7 and 1.5±0.7 for the benign lesions, 0.70±0.28, 5.0±2.6 and 3.1±1.7 for the borderline lesions, and 0.73±0.18, 4.7±2.5 and 3.2±1.6 for the malignant lesions, respectively. Receiver operating characteristic analysis revealed the areas under the curves for detecting non-benign (malignant or borderline) lesions through visual analysis, SUVmax, and SUVmean were 0.914, 0.954, and 0.875, respectively. Conclusion For a variety of pancreatic lesions other than invasive ductal carcinoma, visual analysis and semi-quantitative analyses all showed strong diagnostic performance. However, semi-quantitative analysis with SUVmax proved to be the most effective method for detecting non-benign pancreatic lesions.
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| Journal Title |
The Journal of Medical Investigation
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| ISSN | 13496867
13431420
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| NCID | AA12022913
AA11166929
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| Publisher | Tokushima University Faculty of Medicine
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| Volume | 61
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| Issue | 1-2
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| Start Page | 171
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| End Page | 179
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| Sort Key | 171
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| Published Date | 2014-02
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| Remark | 内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201405131012.pdf 論文本文 : k2748_fulltext.pdf 本論文は，著者Yoichi Otomiの学位論文として提出され，学位審査・授与の対象となっている。 著者の申請により要約(2014-07-24公開)に替えて論文全文を公開(2019-12-19) |
| EDB ID | |
| DOI (Published Version) | |
| URL ( Publisher's Version ) | |
| FullText File | |
| language |
eng
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| TextVersion |
ETD
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| MEXT report number | 甲第2748号
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| Diploma Number | 甲医第1209号
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| Granted Date | 2014-03-24
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| Degree Name |
Doctor of Medical Science
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| Grantor |
Tokushima University
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| departments |
University Hospital
Medical Sciences
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