ID | 116721 |
Title Alternative | Metastatic Primary Splenic Angiosarcoma
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Author |
Miyamoto, Hiroshi
Tokushima University
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Tomonari, Tetsu
Tokushima University
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Okamoto, Koichi
Tokushima University
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Sogabe, Masahiro
Tokushima University
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Muguruma, Naoki
Tokushima University
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Bando, Yoshimi
Tokushima University
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Keywords | Angiosarcoma
Hepatic metastasis
Bone metastasis
Paclitaxel
Chemotherapy
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Content Type |
Journal Article
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Description | A primary splenic angiosarcoma is a rare type of soft tissue sarcoma and is associated with an extremely poor prognosis. In this study, we describe the case of a patient who was diagnosed with metastatic primary splenic angiosarcoma and survived for about 2 years. A 62-year-old female was referred to us for the treatment of splenic angiosarcoma with disseminated intravascular coagulation (DIC) and multiple liver and bone metastases. Paclitaxel therapy resulted in recovery from DIC and enabled her to continue sequential treatment through to sixth-line chemotherapy. We reviewed all splenic angiosarcoma case reports which were described as stage IV to date and compared with our case. From these data, we found that the median overall survival was 105 days, and the prognosis of splenic angiosarcoma of stage IV was worse than conventional case series. Splenectomy was performed in more patients than chemotherapy as a treatment. Moreover, various chemotherapeutic regimens were used. These data suggest that administering chemotherapy including paclitaxel to patients with splenic angiosarcoma might improve their prognosis.
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Journal Title |
Case Reports in Gastroenterology
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ISSN | 16620631
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NCID | AA12780911
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Publisher | S. Karger AG, Basel
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Volume | 15
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Issue | 3
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Start Page | 910
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End Page | 918
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Published Date | 2021-10-11
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Rights | This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
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EDB ID | |
DOI (Published Version) | |
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language |
eng
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TextVersion |
Publisher
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departments |
Medical Sciences
University Hospital
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