直近一年間の累計
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ID 118911
著者
Yamaguchi, Satoshi Fukushima Medical University|Nakagami Hospital
Maeda, Minetaka Yuuai Medical Center
Oba, Kageyuki Yuuai Medical Center
Maimaituxun, Gulinu Fukushima Medical University
Arasaki, Osamu Yuuai Medical Center
福田, 大受 Osaka Metropolitan University KAKEN研究者をさがす
Masuzaki, Hiroaki University of the Ryukyus
島袋, 充生 Fukushima Medical University KAKEN研究者をさがす
キーワード
Epicardial adipose tissue
Left atrial volume index
Sex difference
Atrial fibrillation
資料タイプ
学術雑誌論文
抄録
Background
Sex disparities in the association between epicardial adipose tissue volume (EATV) and cardiovascular disease have been reported. The sex-dependent effects of EATV on left atrial (LA) size have not been elucidated.
Methods
Consecutive 247 subjects (median 65 [interquartile range 57, 75] years; 67% of men) who underwent multi-detector computed tomography without significant coronary artery disease or moderate to severe valvular disease were divided into two groups: patients with sinus rhythm (SR) or atrial fibrillation (AF). Sex differences in the association between the EATV index (EATVI) (mL/m2) and LA volume index (LAVI) in 63 SR (28 men and 35 women) and 184 AF (137 men and 47 women) patients were evaluated using univariate and multivariate regression analyses.
Results
In overall that includes both men and women, the relationship between EATVI and LAVI was not significantly correlated for patients with SR and AF. The relationship between EATVI and LAVI differed between men and women in both SR and AF groups. In SR patients, there was a positive relationship between EATVI and LAVI in men, but not in women. In contrast, in patients with AF, a negative relationship was found between EATVI and LAVI in women, whereas no association was found in men.
Conclusions
We evaluated sex differences in the association between EATVI and LAVI in patients with either SR or AF, and found a positive relationship in men with SR and a negative relationship in women with AF. This is the first report to evaluate sex differences in the relationship between EATVI and LAVI, suggesting that EAT may play a role, at least in part, in sex differences in the etiology of AF.
掲載誌名
BMC Cardiovascular Disorders
ISSN
14712261
cat書誌ID
AA12034774
出版者
BioMed Central|Springer Nature
24
開始ページ
46
発行日
2024-01-13
権利情報
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
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フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系
病院