ID | 113221 |
タイトル別表記 | Combined Predictors for AF
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著者 |
Bando, Sachiko
Tokushima University
Matsumoto, Kazuhisa
Tokushima University
Nagano, Hiromi
Tokushima University
Uematsu, Etsuko
Tokushima University
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キーワード | Atrial fibrillation
Left atrial diameter
Premature atrial contraction
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資料タイプ |
学術雑誌論文
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抄録 | Background: The ability to identify risk markers for new-onset atrial fibrillation (AF) is critical to the development of preventive strategies, but it remains unknown whether a combination of clinical, electrocardiographic, and echocardiographic parameters predicts the onset of AF. In the present study, we evaluated the predictive value of a combined score that includes these parameters.
Methods and Results: We retrospectively studied 1,040 patients without AF who underwent both echocardiography and 24-h Holter electrocardiography between May 2005 and December 2010. During a median follow-up period of 68.4 months (IQR, 49.9–93.3 months), we investigated the incidence of new-onset AF. Of the 1,040 patients, 103 (9.9%) developed AF. Patients who developed AF were older than patients who did not. Total heart beats, premature atrial contraction (PAC) count, maximum RR interval, and frequency of sinus pause quantified on 24-h electrocardiography were associated with new-onset AF. LA diameter (LAD) on echocardiography was also associated with the development of AF. On multivariate Cox analysis, age ≥58 years, PAC count ≥80 beats/day, maximum RR interval ≥1.64 s, and LAD ≥4.5 cm were independently associated with the development of AF. The incidence rate of new-onset AF significantly increased as the combined score (i.e., the sum of the risk score determined using hazard ratios) increased. Conclusions: A combined score that includes age, PAC count, maximum RR interval, and LAD could help characterize the risk of new-onset AF. |
掲載誌名 |
Circulation Journal
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ISSN | 13469843
13474820
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cat書誌ID | AA11591968
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出版者 | The Japanese Circulation Society
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巻 | 82
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号 | 9
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開始ページ | 2253
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終了ページ | 2258
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発行日 | 2018-05-30
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EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
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著者版フラグ |
出版社版
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部局 |
医学系
病院
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