ID | 114642 |
タイトル別表記 | UVA-LED照射装置を用いた、基質特異性拡張型βラクタマーゼ産生大腸菌の殺菌
Inactivation of ESBL-E. coli
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著者 |
ウルファ, マリア
徳島大学大学院栄養生命科学教育部(人間栄養科学専攻)
Sato, Masami
Tokushima University
Fukushima, Shiho
Tokushima University
Kido, Junko
Tokushima University
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キーワード | extended-spectrum β-lactamase (ESBL)
ESBL-E. coli
E. coli
UVA-LED irradiation
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資料タイプ |
学位論文
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抄録 | The prevalence of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli is increasing rapidly and spreading worldwide, particularly in Asia, compared to other regions. In the last ten years, in our hospital, in particular, there has been a < 30% increase. To prevent the spread of ESBL in hospitals and the community, the ultraviolet (UV) A-light-emitting diode (LED) irradiation device was used to inactivate ESBL-E. coli in human livestock and the environment. ESBL-E. coli and E. coli bacterial samples were collected from patients at Tokushima University Hospital (Tokushima City, Japan). The UVA-LED irradiation system had 365 nm single wavelength, and the current of the circuit was set to 0.23 or 0.50 A consistently. Results demonstrated that UVA-LED was useful for the inactivation of ESBL-E. coli and E. coli. The minimum energy dosage required to inactivate ESBL-E. coli and E. coli was 40.76 J/cm2 (45 min) in the first type of UVA-LED and 38.85 J/cm2 (5 min) in the second type. There were no significant differences between ESBL-E. coli and E. coli. The inactivation of ESBL-E. coli was dependent on energy. These findings suggest that UVA-LED with 365 nm single wavelength could be useful for surface decontamination in healthcare facilities.
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掲載誌名 |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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cat書誌ID | AA12022913
AA11166929
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出版者 | Tokushima University Faculty of Medicine
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巻 | 67
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号 | 1-2
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開始ページ | 163
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終了ページ | 169
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並び順 | 163
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発行日 | 2020-02
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備考 | 内容要旨・審査要旨・論文本文の公開
本論文は, 著者Maria Ulfaの学位論文として提出され, 学位審査・授与の対象となっている。 |
EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
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著者版フラグ |
博士論文全文を含む
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文科省報告番号 | 甲第3410号
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学位記番号 | 甲栄第271号
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学位授与年月日 | 2020-03-23
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学位名 |
博士(栄養学)
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学位授与機関 |
徳島大学
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部局 |
病院
医学系
理工学系
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