直近一年間の累計
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ID 118071
著者
曽我部, 正弘 Tokushima University|Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers 徳島大学 教育研究者総覧 KAKEN研究者をさがす
岡久, 稔也 Tokushima University|Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers 徳島大学 教育研究者総覧 KAKEN研究者をさがす
香川, 美和子 Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers
上田, 浩之 Tokushima University|Shikoku Central Hospital of the Mutual Aid Association of Public School Teachers
Kagemoto, Kaizo Tokushima University
Nakasono, Masahiko Tsurugi Municipal Handa Hospital
キーワード
erosive esophagitis
alcohol intake
development
sex
age
資料タイプ
学術雑誌論文
抄録
The influence of changes in alcohol consumption on erosive esophagitis (EE) development in both sexes is unclear. This observational study investigated sex differences in the influence of alcohol consumption on EE development, and included 2582 patients without EE at baseline from 13,448 patients who underwent >2 health check-ups over >1 year. The rates of non-drinkers who started drinking, and drinkers who abstained from drinking, who increased, and who decreased their weekly alcohol consumption were 7.2%, 9.7%, 14.7%, and 24.1% and 7.3%, 17.8%, 12.8%, and 39.0% in men and women, respectively. In the final cohort, 211/1405 (15.0%) men and 79/1177 (6.7%) women newly developed EE. The odds ratio (OR) for drinking in EE development was 1.252 (95% confidence interval (CI), 0.907–1.726) among men and 1.078 (95% CI, 0.666–1.747) among women. Among men aged <50 years, the OR for drinking ≥70 g/week in EE development was 2.825 (95% CI, 1.427–5.592), whereas among women, the OR for drinking ≥140 g/week in EE development was 3.248 (95% CI, 1.646–6.410). Among participants aged <50 years, the OR for daily drinking in EE development was 2.692 (95% CI, 1.298–5.586) among men and 4.030 (95% CI, 1.404–11.57) among women. The influence of alcohol consumption on EE development differed between the sexes. We recommend no alcohol consumption for individuals aged <50 years to avoid EE development. Daily drinkers should be assessed for EE development.
掲載誌名
Nutrients
ISSN
20726643
出版者
MDPI
14
22
開始ページ
4760
発行日
2022-11-10
権利情報
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系
病院