ID | 110426 |
タイトルヨミ | ゲンパツセイ アルドステロンショウ ノ シンダン ニ ユウヨウナ リンショウ ショケン ノ ケントウ
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タイトル別表記 | Clinical parameters for diagnosis of primary aldosteronism
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著者 |
村上, 貴寛
徳島大学病院卒後臨床研修センター
島袋, 充生
徳島大学病院循環器内科
春藤, 譲治
春藤内科胃腸科
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キーワード | Primary aldosteronism
PAC/PRA
low serum potassium
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資料タイプ |
学術雑誌論文
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抄録 | Primary aldosteronism(PA)is known as a secondary hypertension. Hypertensive patients are screened by the plasma aldosterone concentration(PAC)/plasma renin activity(PRA)ratio as a case-detection test for PA. However, clinical parameters for screening patients with primary aldosteronism who need adrenalectomy have not been fully elucidated. We report a case of PA who received endoscopic adrenalectomy and evaluated the clinical parameters for screening patients with primary aldosteronism who need adrenalectomy, retrospectively. We evaluated43patients with PAC/PRA>200as a screening test for PA. Thirty-three(77%) patients were diagnoses as PA after confirmation test. In18patients who received adrenal vein sampling, 10 patients were diagnoses as unilateral adrenal adenoma. We compared clinical parameters between PA and non-PA. The level of PAC was lower in patients with PA compared to that in patients with non-PA. There were no significant change in the level of PAC, PAC/PRA, serum potassium, and blood pressure. PAC and PAC/PRA were higher and serum potassium was lower in patients who received adrenalectomy compared to those in patients without adrenalectomy. ROC curve showed that PAC>200 pg/mL and serum potassium <3.5mEq/L were useful parameters to predict diagnosis of PA who need adrenalectomy. In conclusion, PA patients with PAC>200pg/mL and serum potassium <3.5mEq/L should be considered as candidates for adrenorectomy.
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掲載誌名 |
四国医学雑誌
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ISSN | 00373699
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cat書誌ID | AN00102041
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出版者 | 徳島医学会
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巻 | 73
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号 | 1-2
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開始ページ | 113
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終了ページ | 116
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並び順 | 113
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発行日 | 2017-04-25
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フルテキストファイル | |
言語 |
jpn
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著者版フラグ |
出版社版
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部局 |
医学系
病院
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