ID | 97857 |
タイトルヨミ | シン サルコイドーシス シンダン ノ テビキ ニオケル カクシュ シンダン モダリティー ノ ケントウ
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タイトル別表記 | Validation of diagnostic tests for diagnosing cardiac sarcoidosis
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著者 |
高島, 啓
徳島大学病院循環器内科
山崎, 宙
徳島大学病院循環器内科
小笠原, 梢
徳島大学病院循環器内科
坂東, 左知子
徳島大学病院循環器内科
仁木, 敏之
徳島大学病院循環器内科
上田, 由佳
徳島大学病院卒後臨床研修センター|徳島大学病院循環器内科
冨田, 紀子
徳島大学病院循環器内科
能勢, 隼人
徳島大学病院放射線科
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キーワード | cardiac sarcoidosis
cardiac magnetic resonance imaging
late gadolinium enhancement
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資料タイプ |
学術雑誌論文
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抄録 | Background : Sarcoidosis is a multiple organ granulomatous disease of undefined cause. Although cardiac involvement often leads to adverse outcomes in patients with sarcoidosis, diagnosis of cardiac sarcoidosis(CS)remains difficult due to the lack of sensitive diagnostic tests.
Purpose : To determine an appropriate combination of diagnostic tests for detecting CS. Method and Results : Thirteen patients were diagnosed with CS from December 2006 to November2010by the use of2006revised guidelines for diagnosing CS of the Japanese Society of Sarcoidosis and Other Granulomatous Disorders. Positive rate of each major or minor criterion in the guidelines was examined. We also evaluated positive rate of each diagnostic test. In the major criteria, basal thinning of the ventricular septum showed a high positive rate of71.4%, although the others were less than50%. In the minor criteria, positive rates of abnormal electrocardiogram findings and abnormal echocardiogram were76.9% and84.6%, respectively. Late gadolinium enhancement (LGE)of the myocardium on cardiac MRI scanning(CMR)showed a positive rate of100% ; however, CMR was not performed in four patients due to life-threatening arrhythmia. All13patients showed abnormal findings at least in either echocardiogram or LGE on CMR. Conclusion : Echocardiography is a convenient diagnostic test for detecting CS. The combination of cardiac MRI and echocardiography may improve diagnostic sensitivity. |
掲載誌名 |
四国医学雑誌
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ISSN | 00373699
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cat書誌ID | AN00102041
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出版者 | 徳島医学会
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巻 | 67
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号 | 5-6
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開始ページ | 253
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終了ページ | 256
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並び順 | 253
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発行日 | 2011-12-25
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備考 | |
フルテキストファイル | |
言語 |
jpn
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部局 |
病院
医学系
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