ID 109546
Author
Otomi, Yoichi Department of Radiology, Institute of Health Bioscience, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Otsuka, Hideki Department of Medical Imaging, Institute of Health Bioscience, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Terazawa, Kaori Department of Radiology, Institute of Health Bioscience, the University of Tokushima Graduate School
Nose, Hayato Department of Radiology, Institute of Health Bioscience, the University of Tokushima Graduate School
Kubo, Michiko Department of Radiology, Institute of Health Bioscience, the University of Tokushima Graduate School
Matsuzaki, Kenji Department of Radiology, Institute of Health Bioscience, the University of Tokushima Graduate School KAKEN Search Researchers
Ikushima, Hitoshi Department of Radiation Therapy Technology, Institute of Health Bioscience, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Bando, Yoshimi Department of Molecular and Environmental Pathology, Institute of Health Bioscience, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Harada, Masafumi Department of Radiology, Institute of Health Bioscience, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
FDG
PET/CT
pancreatic lesion
Content Type
Journal Article
Description
Introduction The utility of FDG PET/CT for the detection and evaluation of invasive ductal carcinoma has been widely reported, but a few studies have assessed the utility of FDG PET/CT to detect malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Purpose To compare the diagnostic performance of visual estimation with the semi-quantitative scores of FDG PET/CT for detecting malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Material and Methods Images of pathologically proven pancreatic lesions from 32 patients were retrospectively evaluated : 14 benign lesions, 7 borderline (lowmalignant) lesions, and 11 malignant lesions. The average scores from visual estimation by the two observers were compared to two semiquantiative analyses of FDG uptake in the lesions, namely the maximum standardized uptake value (SUVmax) and mean standardized uptake value (SUVmean). Results Visual analysis value, SUVmax and SUVmean were 0.33±0.21, 1.8±0.7 and 1.5±0.7 for the benign lesions, 0.70±0.28, 5.0±2.6 and 3.1±1.7 for the borderline lesions, and 0.73±0.18, 4.7±2.5 and 3.2±1.6 for the malignant lesions, respectively. Receiver operating characteristic analysis revealed the areas under the curves for detecting non-benign (malignant or borderline) lesions through visual analysis, SUVmax, and SUVmean were 0.914, 0.954, and 0.875, respectively. Conclusion For a variety of pancreatic lesions other than invasive ductal carcinoma, visual analysis and semiquantitative analyses all showed strong diagnostic performance. However, semiquantitative analysis with SUVmax proved to be the most effective method for detecting non-benign pancreatic lesions.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
61
Issue
1-2
Start Page
171
End Page
179
Sort Key
171
Published Date
2014-02
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
University Hospital
Medical Sciences