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ID 116019
Title Alternative
CHH with Early-Onset CAD
Author
Takashima, Akira Kitajima Taoka Hospital|Tokushima University
Kojima, Yuko Tokushima University
Zheng, Robert Tokushima University
Keywords
congenital hypogonadotropic hypogonadism
coronary artery disease
diabetes mellitus
Kallmann syndrome
testosterone
Content Type
Journal Article
Description
The patient with congenital hypogonadotropic hypogonadism (HH) shows low serum levels of androgen, which is a group of sex hormones including testosterone, caused by the decreased gonadotropin release in the hypothalamus. Recent reports showed androgens exert protective effects against insulin resistance or atherosclerotic diseases, such as diabetes mellitus or coronary artery disease. However, whether the juvenile hypogonadism affects the diabetes or cardiovascular disease is unclear. We report a case of a middle-aged man with congenital HH who had severe coronary artery disease complicated with metabolic disorders.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
68
Issue
1-2
Start Page
189
End Page
191
Sort Key
189
Published Date
2021-02
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences
University Hospital