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ID 114198
Author
Nishiyama, Seiichi Shikoku Central Hospital
Abe, Toshio Shikoku Central Hospital
Content Type
Journal Article
Description
A Antiphospholipid syndrome (APS) is a systemic autoimmune disease characterized by thrombembolic events including thromboembolism (VTE) in association with the presence of antiphospholipid antibodies. The standard treatment of VTE historically consists of anticoagulation therapy with warfarin, a vitamin K antagonist. Recently, direct oral anticoagulants, including rivaroxaban have become available for the treatment of VTE. However, the choice of anticoagulant, and the duration of anticoagulation in patients with APS has not been determined yet due to lack of evidence. Here, we report a case of recurrent venous thrombosis after discontinuation of rivaroxaban therapy and avoiding sedentary life style in a patient with APS. We suggest that indefinite anticoagulation therapy might be needed even in low risk APS cases.
Journal Title
BMJ Case Reports
ISSN
1757790X
NCID
AA12533286
Publisher
BMJ Publishing Group
Volume
12
Issue
1
Start Page
e227663
Published Date
2019-01-10
Rights
This article has been accepted for publication in BMJ Case Reports, 2019 following peer review, and the Version of Record can be accessed online at https://doi.org/10.1136/bcr-2018-227663.
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DOI (Published Version)
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language
eng
TextVersion
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departments
Medical Sciences