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ID 111628
Title Alternative
神経性やせ症患者のQOLに影響を与える臨床的要因
Author
Kane, Chikako Tokushima University
Hamatani, Sayo Chiba University
Keywords
Anorexia nervosa
Quality of Life
Influencing Factor
Depression
Interoceptive Confusion
Content Type
Thesis or Dissertation
Description
Objective: The purpose of this study was to elucidate clinical factors influencing quality of life (QOL) in anorexia nervosa (AN) patients. Methods: Twenty female patients with AN (median age = 30.0 years, quartile deviation = 6.8) and forty female healthy controls (HC) (median age = 30.0 years, quartile deviation = 8.6) participated in the study. QOL was assessed with the 36-Item Short Form Health Survey (SF-36) and social support was evaluated using the Multidimensional Scale of Perceived Social Support (MSPSS). Clinical symptoms were evaluated with the Structured Interview Guide for the Hamilton Depression Rating Scale (SIGH-D) and the Eating Disorder Inventory-2 (EDI-2). Results: Scores of the SF-36 Mental Component Summary (MCS) (U = 124.0, P < 0.0001) and Role/Social Component Summary (RCS) (U = 223.0, P = 0.006) and scores of total (U = 108.0, P < 0.0001) and subscales of the MSPSS were lower in AN group than HC group, and the SIGH-D score was higher (U = 46.0, P < 0.0001) in AN group than HC group. Scores of the SIGH-D (ρ = −0.565, P < 0.05) and subscales of the EDI-2 Interoceptive Confusion (ρ = −0.556, P < 0.05), Interpersonal Difficulty (ρ = −0.581, P < 0.05) and Negative Self-image (ρ = −0.617, P < 0.05) were negatively correlated to MCS, and score of Interoceptive Confusion subscale showed a negative correlation to RCS (ρ = −0.672, P < 0.05). Moreover, stepwise regression analysis showed that the SIGH-D score was an independent predictor of MCS and Interoceptive Confusion score predicted RCS. Conclusion: These results suggest that among a variety of clinical symptoms and psychopathologies, depressive symptoms, poor emotional awareness and impaired sense of control are the most important influencing factors on AN patients’ QOL.
Journal Title
Open Journal of Psychiatry
ISSN
21617325
21617333
Publisher
Scientific Research Publishing
Volume
8
Issue
1
Start Page
50
End Page
60
Published Date
2017-12-27
Remark
内容要旨・審査要旨・論文本文の公開
本論文は, 著者Chikako Kaneの学位論文として提出され, 学位審査・授与の対象となっている。
Rights
© 2018 by authors and Scientific Research Publishing Inc. This work is licensed under the Creative Commons Attribution International License (CC BY 4.0). http://creativecommons.org/licenses/by/4.0/
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第3154号
Diploma Number
甲保第34号
Granted Date
2018-03-23
Degree Name
Doctor of Health Science
Grantor
Tokushima University
departments
Medical Sciences