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ID 114202
Title Alternative
Adipose Tissue and Atherosclerosis
Author
Tanaka, Kimie The University of Tokyo
Keywords
Atherosclerosis
Adipose tissue
Adipocytokine
Content Type
Journal Article
Description
Accumulating evidence revealed that adipose tissues secrete pro-inflammatory and anti-inflammatory humoral factors, called as adipocytokines. Most of the arteries are surrounded by perivascular adipose tissue (PVAT), which influences adjacent artery by secreting adipocytokines. PVATs are supposed to be athero-protective under healthy conditions, whereas PVATs are athero-promoting in obesity. Recent clinical studies suggested that coronary atherosclerosis is associated with increased volume of epicardial adipose tissue (EAT), PVAT of coronary artery. It was suggested that enhanced inflammation in EAT is also associated with vasospastic angina. In this review article, we will summarize recent findings about potential roles of EAT in the pathogenesis of coronary atherosclerosis.
Journal Title
Annals of Nuclear Cardiology
ISSN
24241741
21893926
Publisher
The Japanese Society of NuclearCar diology
Volume
4
Issue
1
Start Page
5
End Page
10
Published Date
2018-08-31
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Author
departments
Medical Sciences