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ID 116106
著者
板東, 浩 Tokushima University|Japan Low Carbohydrate Diet Promotion Association KAKEN研究者をさがす
キーワード
Oral hypoglycemic agents (OHAs)
Sodium glucose cotransporter-2 inhibitor (SGLT-2i)
Semaglutide
Bullous pemphigoid (BP)
Hospitalization for heart failure (HHF)
Major adverse cardiovascular event (MACE)
資料タイプ
学術雑誌論文
抄録
Current reports for oral hypoglycemic agents (OHAs) are described. As to the association of dipeptidyl peptidase-4 inhibitors (DPP-4i) and bullous pemphigoid (BP), odds ratio (OR) was vildagliptin 5.08, linagliptin 2.87, sitagliptin 1.29 (not significant). Regarding the comparative study between SGLT2i and DPP-4i, SGLT2i group showed lower hazard ratio (HR) as MACE 0.76, myocardial infarction 0.82, cardiovascular death 0.60, heart failure 0.43, all-cause mortality 0.60. Semaglutide showed reduced OR for cardiovascular death than exenatide 0.47, dulaglutide 0.46, albiglutide 0.45, lixisenatide 0.43. SGLT2i showed reduction risk of HR for MACE 0.90, hospitalization for heart failure (HHF)/cardiovascular death 0.78, renal outcomes 0.62.
掲載誌名
Diabetes Research : Open Journal
ISSN
23796375
出版者
Openventio Publishers
7
1
開始ページ
e1
終了ページ
e3
発行日
2021-06-11
権利情報
This is an open-access article distributed under Creative Commons Attribution 4.0 International License (CC BY 4.0)(https://creativecommons.org/licenses/by/4.0/), which allows to copy, redistribute, remix, transform, and reproduce in any medium or format, even commercially, provided the original work is properly cited.
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フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系