直近一年間の累計
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ID 113702
著者
板東, 浩 Tokushima University|Japan Low Carbohydrate Diet Promotion Association KAKEN研究者をさがす
Ebe, Koji Japan Low Carbohydrate Diet Promotion Association|Takao Hospital
Muneta, Tetsuo Japan Low Carbohydrate Diet Promotion Association|Muneta Maternity Clinic
板東, 正浩 Tokushima University
Yonei, Yoshikazu Doshisha University
キーワード
Morbus value (M value)
Type 2 diabetes mellitus (T2DM)
Low carbohydrate diet (LCD)
Daily profile of blood glucose
Homeostasis model assessment of insulin resistance (HOMA-R)
Homeostasis model assessment of β cell function (HOMA-β)
資料タイプ
学術雑誌論文
抄録
Background: There are discussion of Calorie Restriction (CR) and Low Carbohydrate Diet (LCD). Authors and colleagues have continued research concerning LCD, CR and Morbus (M) value. Furthermore, this study also included homeostasis model assessment (HOMA).
Subjects and Methods: Subjects enrolled were 40 type 2 diabetes mellitus (T2DM) cases with more than 10 μU/mL of fasting immunoreacitve insulin (IRI). Methods included fundamental tests such as glucose, IRI, HOMA-R, HOMA-β, average blood glucose on day 2 and 14 during CR and LCD meal.
Results: Current data were in the following: average age 56.8 ± 12.3 years old, median values are HbA1c 7.2%, fasting glucose 141 mg/dL, IRI 13.1 μU/mL, HOMA-R 4.6, HOMA-β 57.1. Median values on day 2 vs 14 were average blood glucose 160 vs 120 mg/dL, M value 37.1 vs 7.4, Triglyceride 137 vs 97 mg/dL, respectively. M value showed significant correlation with HOMA-R (p<0.05) and HOMA-β (p<0.01).
Discussion and Conclusion: The results suggested that LCD showed clinical effect for decreasing of glucose and M value in glucose variability and those patients would have insulin resistance and decreased β cell function. Furthermore, these findings would become basal and useful data for future research in this field.
掲載誌名
Clinical Case Reports : Open Access
出版者
Yumed Text
1
1
開始ページ
103
発行日
2018-08-31
権利情報
Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License(https://creativecommons.org/licenses/by-nc-sa/4.0/).
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
医学系