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ID 114397
著者
髙士, 祐一 The University of Tokyo
Kinoshita, Yuka The University of Tokyo
Ito, Nobuaki The University of Tokyo
Taguchi, Manabu The University of Tokyo
Takahashi, Masaaki The University of Tokyo
Egami, Naoya The University of Tokyo
Tajima, Shogo The University of Tokyo
Nangaku, Masaomi The University of Tokyo
キーワード
tumor-induced osteomalacia
fibroblast growth factor 23
phosphaturic mesenchymal tumor mixed connective tissue variant
parotid gland
資料タイプ
学術雑誌論文
抄録
A 77-year-old man was suspected of having tumor-induced osteomalacia (TIO) because of hypophosphatemia (1.9 mg/dL) and elevated serum fibroblast growth factor 23 (FGF23) level (186.9 pg/mL). We detected a tumor in his left parotid gland, and the FGF23 level in the left external jugular vein indicated that the tumor overproduced FGF23. After the removal of the tumor, the serum FGF23 level rapidly decreased, and the serum phosphate normalized. This is the first case of TIO caused by a tumor in a parotid gland. This case indicates that the responsible tumors for TIO can be quite diverse.
掲載誌名
Internal Medicine
ISSN
13497235
出版者
The Japanese Society of Internal Medicine
56
5
開始ページ
535
終了ページ
539
発行日
2017-03-01
権利情報
The Internal Medicine is an Open Access article distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
先端酵素学研究所