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ID 106142
タイトル別表記
軟部病変におけるF-18 FDG PET/CTと病理所見との相関関係
FDG-PET/CT findings of soft tissue lesoions
著者
能勢, 隼人 徳島大学大学院医科学教育部(医学専攻)
Terazawa, Kaori The University of Tokushima
キーワード
F-18 FDG PET
soft tissue tumor
myxoid tumor
neurogenic tumor
liposarcoma
資料タイプ
学位論文
抄録
Objective : To evaluate the correlations between F-18 FDG uptake imaged with PET/CT and pathological findings in soft tissue lesions. Methods : Fifty-four soft tissue lesions in 47 patients were evaluated. The correlations between the degree of FDG uptake, pathological type and grade, and MRI signal intensity and/or enhancement pattern were evaluated. Tumor FDG uptake was quantified by the maximum standardized uptake value (SUVmax). Results : Thirty-one lesions were malignant and twenty-three lesions were benign. The difference between SUVmax in the malignant and benign groups was statistically significant (p<0.001). Malignant myxoid lesions and well differentiated liposarcoma showed low FDG uptake. Benign neurogenic lesions showed low FDG uptake while malignant neurogenic tumors showed high FDG uptake, and the difference between SUVmax in the benign and malignant lesions was statistically significant (p<0.001). In a neurofibromatosis type-1 patient who had multiple neurogenic tumors, FDG-PET/CT could distinguish malignant peripheral nerve sheath tumors from other benign lesions with similar MRI findings. Conclusions : FDG-PET/CT is useful for differentiating malignant from benign soft tissue lesions, but malignant soft tissue lesions may show various patterns on FDG-PET, and MRI may be helpful for a differential diagnosis.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA12022913
AA11166929
出版者
Tokushima University Faculty of Medicine
60
3-4
開始ページ
184
終了ページ
190
並び順
184
発行日
2013-08
備考
内容要旨・審査要旨・論文本文の公開
内容要旨・審査要旨 : LID201405131013.pdf
論文本文 : k2749_fulltext.pdf
本論文は,著者Hayato Noseの学位論文として提出され,学位審査・授与の対象となっている。
著者の申請により要約(2014-05-23公開)に替えて論文全文を公開(2019-12-20)
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第2749号
学位記番号
甲医第1210号
学位授与年月日
2014-03-24
学位名
博士(医学)
学位授与機関
徳島大学
部局
医学系
病院