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ID 113813
著者
Akita, Kazuya Tokushima University
Kamada, Kumiko Tokushima University
Ishikawa, Kunio Kyushu University
キーワード
carbonate apatite
hydroxyapatite
osteoconductivity
bone substitute
資料タイプ
学術雑誌論文
抄録
Since bone apatite is a carbonate apatite containing carbonate in an apatitic structure, carbonate content may be one of the factors governing the osteoconductivity of apatitic bone substitutes. The aim of this study was to evaluate the effects of carbonate content on the osteoconductivity of apatitic bone substitutes using three commercially available bone substitutes for the reconstruction of alveolar bone defects of a beagle mandible with simultaneous dental implant installation. NEOBONE®, Bio-Oss®, and Cytrans® that contain 0.1 mass%, 5.5 mass%, and 12.0 mass% of carbonate, respectively, were used in this study. The amount of newly formed bone in the upper portion of the alveolar bone defect of the beagle’s mandible was 0.7%, 6.6%, and 39.4% at 4 weeks after surgery and 4.7%, 39.5% and 75.2% at 12 weeks after surgery for NEOBONE®, Bio-Oss®, and Cytrans®, respectively. The results indicate that bone-to-implant contact ratio was the largest for Cytrans®. Additionally, the continuity of the alveolar ridge was restored in the case of Cytrans®, whereas the continuity of the alveolar ridge was not sufficient when using NEOBONE® and Bio-Oss®. Both Cytrans® and Bio-Oss® that has a relatively larger carbonate content in their apatitic structure was resorbed with time. We concluded that carbonate content is one of important factors governing the osteoconductivity of apatitic bone substitutes.
掲載誌名
Journal of Biomedical Materials Research Part B : Applied Biomaterials
ISSN
15524973
15524981
cat書誌ID
AA11881538
AA12001425
出版者
John Wiley & Sons
108
4
開始ページ
1450
終了ページ
1459
発行日
2019-10-17
備考
This is the peer reviewed version of the following article: Mano, T, Akita, K, Fukuda, N, et al. Histological comparison of three apatitic bone substitutes with different carbonate contents in alveolar bone defects in a beagle mandible with simultaneous implant installation. J Biomed Mater Res. 2020; 108: 1450– 1459, which has been published in final form at https://doi.org/10.1002/jbm.b.34492. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions.
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フルテキストファイル
言語
eng
著者版フラグ
著者版
部局
歯学系