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ID 114357
タイトル別表記
REARRANGEMENT OF c-myc GENE
著者
Shiraishi, Masahiko National Cancer Center Research Institute
Hirohashi, Setsuo National Cancer Center Research Institute
Morinaga, Shojiroh National Cancer Center Research Institute
Shimosato, Yukio National Cancer Center Research Institute
Sugimura, Takashi National Cancer Center Research Institute
Sekiya, Takao National Cancer Center Research Institute
キーワード
c-myc
Rearrangement of gene
Giant cell carcinoma of the lung
資料タイプ
学術雑誌論文
抄録
The c-myc oncogene was found to be rearranged in a human cell line of giant cell carcinoma of the lung (C-Lu65) and in a human primary giant cell carcinoma of the lung (LuC38C). The rearrangements in C-Lu65 and LuC38C were in regions about 7.5kb and 6kb, respectively, upstream from the transcription initiation site. No rearrangement of the c-myc gene was observed in a non-cancerous portion (LuC38N) of the lung of the patient who carried LuC38C. These results suggest that rearrangement of the c-myc gene may play some role in tumorigenesis of giant cell carcinoma of the lung.
掲載誌名
Japanese Journal of Cancer Research
ISSN
09105050
cat書誌ID
AA00690844
出版者
Japanese Cancer Association
77
8
開始ページ
731
終了ページ
735
発行日
1986-08
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
出版社版
部局
歯学系