ID | 111103 |
タイトル別表記 | 入院慢性腎臓病患者における血清アルブミン濃度に影響を与える因子
Serum albumin, proteinuria in hospitalized CKD patients
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著者 |
吉本, 咲耶
徳島大学大学院医科学教育部(医学専攻)
上田, 紗代
Tokushima University
小野, 広幸
Tokushima University
西村, 賢二
Tokushima University
Obata, Fumiaki
Tokushima University
Inagaki, Taizo
Tokushima University
Minato, Masanori
Tokushima University
岸, 史
Tokushima University
Hann, Michael
Naval Medical Center San Diego
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キーワード | Serum albumin concentration
Proteinuria
Chronic kidney disease
Postural change
Hospitalization
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資料タイプ |
学位論文
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抄録 | Background : Serum albumin concentration (SAC) is a prognostic factor that is affected by many factors such as postural change, liver function and food intake. Chronic kidney disease (CKD) patients excrete proteinuria, have low-protein diet, and receive glucocorticoid therapy. No one has evaluated the most influential factors on SAC in CKD patients. Methods : A retrospective study. Hospitalized CKD patients with less than 1 g/ gCreatinine proteinuria receiving glucocorticoid therapy (n=28), with 1 or more g/gCreatinine proteinuria not receiving glucocorticoid therapy (n=36), and with 1 or more g/gCreatinine proteinuria receiving glucocorticoid therapy (n=39) were enrolled. SAC, hemoglobin, proteinuria and blood pressure at the last outpatient check-up before hospitalization, on the second day of hospitalization, at the last laboratory examination before discharge, as well as at the first outpatient follow-up after discharge were analyzed. Results : SAC decreased on the second day of hospitalization and increased at the first outpatient follow-up significantly in all groups. Unexpectedly, the change of SAC was irrelevant to the amount of proteinuria. Conclusions : SAC was affected by not only proteinuria, but also postural change, physical activity, and food in CKD patients. SAC should be analyzed by standardizing a patient’s condition during phlebotomy.
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掲載誌名 |
The Journal of Medical Investigation
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ISSN | 13496867
13431420
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cat書誌ID | AA11166929
AA12022913
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出版者 | Faculty of Medicine Tokushima University
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巻 | 64
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号 | 1-2
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開始ページ | 146
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終了ページ | 152
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並び順 | 146
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発行日 | 2017-02
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備考 | 内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨:LID201704171001.pdf 論文本文:LID201704171002.pdf 本論文は,著者Sakiya Yoshimotoの学位論文として提出され,学位審査・授与の対象となっている。 |
EDB ID | |
出版社版DOI | |
出版社版URL | |
フルテキストファイル | |
言語 |
eng
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著者版フラグ |
博士論文全文を含む
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文科省報告番号 | 甲第3029号
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学位記番号 | 甲医第1333号
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学位授与年月日 | 2017-03-23
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学位名 |
博士(医学)
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学位授与機関 |
徳島大学
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部局 |
病院
医学系
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