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ID 111103
タイトル別表記
入院慢性腎臓病患者における血清アルブミン濃度に影響を与える因子
Serum albumin, proteinuria in hospitalized CKD patients
著者
吉本, 咲耶 徳島大学大学院医科学教育部(医学専攻)
上田, 紗代 Tokushima University
小野, 広幸 Tokushima University
西村, 賢二 Tokushima University
Obata, Fumiaki Tokushima University
Inagaki, Taizo Tokushima University
Minato, Masanori Tokushima University
岸, 史 Tokushima University
Hann, Michael Naval Medical Center San Diego
キーワード
Serum albumin concentration
Proteinuria
Chronic kidney disease
Postural change
Hospitalization
資料タイプ
学位論文
抄録
Background : Serum albumin concentration (SAC) is a prognostic factor that is affected by many factors such as postural change, liver function and food intake. Chronic kidney disease (CKD) patients excrete proteinuria, have low-protein diet, and receive glucocorticoid therapy. No one has evaluated the most influential factors on SAC in CKD patients. Methods : A retrospective study. Hospitalized CKD patients with less than 1 g/ gCreatinine proteinuria receiving glucocorticoid therapy (n=28), with 1 or more g/gCreatinine proteinuria not receiving glucocorticoid therapy (n=36), and with 1 or more g/gCreatinine proteinuria receiving glucocorticoid therapy (n=39) were enrolled. SAC, hemoglobin, proteinuria and blood pressure at the last outpatient check-up before hospitalization, on the second day of hospitalization, at the last laboratory examination before discharge, as well as at the first outpatient follow-up after discharge were analyzed. Results : SAC decreased on the second day of hospitalization and increased at the first outpatient follow-up significantly in all groups. Unexpectedly, the change of SAC was irrelevant to the amount of proteinuria. Conclusions : SAC was affected by not only proteinuria, but also postural change, physical activity, and food in CKD patients. SAC should be analyzed by standardizing a patient’s condition during phlebotomy.
掲載誌名
The Journal of Medical Investigation
ISSN
13496867
13431420
cat書誌ID
AA11166929
AA12022913
出版者
Faculty of Medicine Tokushima University
64
1-2
開始ページ
146
終了ページ
152
並び順
146
発行日
2017-02
備考
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨:LID201704171001.pdf
論文本文:LID201704171002.pdf
本論文は,著者Sakiya Yoshimotoの学位論文として提出され,学位審査・授与の対象となっている。
EDB ID
出版社版DOI
出版社版URL
フルテキストファイル
言語
eng
著者版フラグ
博士論文全文を含む
文科省報告番号
甲第3029号
学位記番号
甲医第1333号
学位授与年月日
2017-03-23
学位名
博士(医学)
学位授与機関
徳島大学
部局
病院
医学系