バイアグラ イッパンメイ クエンサン シルデナフィル ノ シヨウ ケイケン ト ゼンゴ ケンキュウ ニヨル コウカ ヒョウカ : ダイ1ペン ライインシャ ノ トクチョウ
An estimate of the effectiveness of Sildenafil Citrate (Viagra®) : Clinical features of outpatients with erectile dysfunction
Ogura, Kunihiro Ogura Shinryosho Clinic
pigmentary retinal degeneration（PRD）
Since Sildenafil became available in Japan five years ago, 208 outpatients with Erectile
Dysfunction（ED）have consulted the Ogura Shinryosho Clinic in Tokushima City, Japan.
On August 31st 1999, an article in the Tokushima Newspaper warned readers of the possible
side effects of Sildenafil including heart attacks. After the publication of this article, the
number of patients in this clinic dropped by 80%. The mean age of the patients in this
study was 57.2 with a distribution between 29 and 84. The morbidity period of ED is 35
months, and it is described as decreasing logarithmically ; only 22 outpatients in this study
experienced symptoms occurring over six years. Several patients in this study experienced
past medical problems including Diabetes Mellitus（18.3%）, heart disease（14.5%）, and
benign prostatic hyperplasia（12.4%）. Pigmentary retinal degeneration（PRD）is classified
as one of Sildenafil’s contraindications. Although no patients experienced PRD in this
study, over 50 male patients in the prefecture of Tokushima have been diagnosed with PRD.
It should be noted that there are possible complications associated with taking Sildenafil
before the onset of PRD and Usher Syndrome.
LID201208281002.pdf 190 KB