ID 102836
Title Transcription
シシツ テイカ リョウホウ ニヨル ケイドウミャク プラーク アンテイカ ノ ヒョウカ : チョウオンパ integrated backscatter オ モチイタ カラー マッピング システム ノ カイハツ ト リンショウ オウヨウ
Title Alternative
Effect of statin therapy on carotid artery plaque assessed by integrated backscatter color mapping : Development of imaging analytical software and its application on3cases
Author
Nishio, Susumu Ultrasound center, Tokushima University Hospital
Tamai, Rina Ultrasound center, Tokushima University Hospital
Hirata, Yukina Ultrasound center, Tokushima University Hospital
Hirota, Daichi Ultrasound center, Tokushima University Hospital
Nakagawa, Maya Ultrasound center, Tokushima University Hospital
Hayashi, Shuji Ultrasound center, Tokushima University Hospital
Tomita, Noriko Department of Cardiology, Tokushima University Hospital
Hotchi, Junko Department of Cardiology, Tokushima University Hospital
Ogasawara, Kozue Department of Cardiology, Tokushima University Hospital
Takashima, Akira Department of Cardiology, Tokushima University Hospital
Yamasaki, Hiromu Department of Cardiology, Tokushima University Hospital
Bando, Sachiko Department of Cardiology, Tokushima University Hospital
Niki, Toshiyuki Department of Cardiology, Tokushima University Hospital
Ueta, Yuka Department of Cardiology, Tokushima University Hospital
Iwase, Takashi Department of Cardiology, Tokushima University Hospital KAKEN Search Researchers
Taketani, Yoshio Department of Cardiology, Tokushima University Hospital KAKEN Search Researchers
Satomi, Junichiro Department of Neurosurgery, Tokushima University Hospital KAKEN Search Researchers
Keywords
IBS(integrated backscatter)
carotid plaque
CEA(carotid endarterectomy)
Content Type
Journal Article
Description
Background : The carotid plaque vulnerability is related to myocardial and cerebral infarction. We intended to develop an imaging system which enables to visualize tissue characteristics in the carotid plaques based on ultrasound integrated backscatter(IB). And to test its clinical efficacy, effect of the statin therapy on the plaques was evaluated with our software. Methods and Results : Carotid ultrasound examination was performed and ultrasonographic RAW data of the plaques were obtained from8patients undergoing carotid artery endarterectomy. Tissue characteristics in the plaques of resected examples were compared with preoperative ultrasonic images and the tissue IB values corresponding to the specimens were determined for developing our imaging system. Using this system, Color-coded maps of plaques in the three patients were constructed before and after lipid lowing therapy. We could demonstrate that lipid fraction in each plaque decreased and fibrous or calcification fraction increased in the follow-up study. Conclusions : Changes in histology of carotid plaques by statin could visualized with our imaging system. This technique may become a useful tool for the management of atherosclerosis.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
68
Issue
3-4
Start Page
147
End Page
152
Sort Key
147
Published Date
2012-08-25
Remark
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
University Hospital
Medical Sciences