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ID 105906
Title Alternative
多巣性運動ニューロパチーは過少診断されているのか? : 日本の疫学調査
Multifocal Motor Neuropathy
Author
Shimatani, Yoshimitsu Tokushima University
Kuwabara, Satoshi Japanese Multifocal Motor Neuropathy Study Group
Imai, Tomihiro Japanese Multifocal Motor Neuropathy Study Group
Baba, Masayuki Japanese Multifocal Motor Neuropathy Study Group
Komori, Tetsuo Japanese Multifocal Motor Neuropathy Study Group
Sonoo, Masahiro Japanese Multifocal Motor Neuropathy Study Group
Mezaki, Takahiro Japanese Multifocal Motor Neuropathy Study Group
Kawamata, Jun Japanese Multifocal Motor Neuropathy Study Group
Hitomi, Takefumi Japanese Multifocal Motor Neuropathy Study Group
Kohara, Nobuo Japanese Multifocal Motor Neuropathy Study Group
Arimura, Kimiyoshi Japanese Multifocal Motor Neuropathy Study Group
Hashimoto, Shuji Fujita Health University School of Medicine
Kusunoki, Susumu Kinki University
Kaji, Ryuji Tokushima University|Japanese Multifocal Motor Neuropathy Study Group Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
multifocal motor neuropathy
amyotrophic lateral sclerosis
diagnosis
conduction block
prevalence
Content Type
Thesis or Dissertation
Description
Objective: Our objective was to do an epidemiologic survey of patients with multifocal motor neuropathy (MMN) in comparison with those with amyotrophic lateral sclerosis (ALS) in Japan.
Methods: In this retrospective study, we examined 46 patients with MMN and 1,051 patients with ALS from major neuromuscular centers in Japan from 2005 to 2009. Diagnosis was based on the European Federation of Neurological Societies/Peripheral Nerve Society (EFNS/PNS) and the revised El Escorial criteria. The efficacy of intravenous immunoglobulin (IVIg) was also taken into consideration in the diagnosis of MMN.
Results: The ratio of MMN to ALS patients (0-0.10) varied among the centers, but mostly converged to 0.05. The prevalence was estimated to be 0.29 MMN patients and 6.63 ALS patients per 100,000 population.
Conclusions: The frequency of MMN patients was around 1 out of 20 ALS patients, and MMN was possibly underdiagnosed in some centers.
Journal Title
Muscle & Nerve
ISSN
10974598
NCID
AA11625800
Publisher
Wiley Periodicals
Volume
49
Issue
3
Start Page
357
End Page
361
Published Date
2013-07-08
Remark
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201310221001.pdf
論文本文 : LID201407091001.pdf
Submitted Version (preprint)
本論文は, 著者Ai Miyashiroの学位論文として提出され, 学位審査・授与の対象となっている。
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第2629号
Diploma Number
甲医第1172号
Granted Date
2013-09-12
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
University Hospital
Medical Sciences