ID 106034
Author
Nakatani, Hajime Department of Surgery, Noichi Central Hospital
Kumon, Tatsuya Department of Surgery, Noichi Central Hospital
Kumon, Masamitsu Department of Surgery, Noichi Central Hospital
Hamada, Shinichi Department of Surgery, Kubokawa Hospital
Okanoue, Toyotake Department of Surgery, Kubokawa Hospital
Kawamura, Akihiro Department of Surgery, Kubokawa Hospital
Nakatani, Kimiko Department of Radiology, Kochi Red Cross Hospital
Hiroi, Makoto Laboratory of Diagnostic Pathology, Kochi Medical School, Kochi University
Hanazaki, Kazuhiro Department of Surgery, Kochi Medical School, Kochi University
Keywords
carcinoembryonic antigen
carbohydrate antigen 19-9
sigmoid colon cancer
Content Type
Journal Article
Description
Carcinoembryonic antigen (CEA) and carbohydrate antigen (CA)19-9 are well known as the most common tumor markers of colon cancer, and levels are used not only for preoperative assessment of extent and outcome of cancer, but also postoperative monitoring of recurrence. We encountered a patient with sigmoid colon cancer showing abnormally high serum levels of CEA (311.1 ng/ml) and CA19-9 (5731.2 U/ml) preoperatively. We could not detect any metastases on computed tomography (CT) or 18F-fluorodeoxyglucose positron emission tomography/CT. Sigmoidectomy and lymph node dissection were performed. Pathological analysis revealed well-differentiated tubular adenocarcinoma of the sigmoid colon with cancer cells infiltrating to the subserosa, but no lymph node metastases. As of postoperative day 60, serum levels of CEA and CA19-9 were 3.4 ng/ml and 9.2 U/ml, respectively, without any further anti-tumor treatment. This represents a rare case of sigmoid colon cancer with high levels of tumor markers in sera that improved following sigmoidectomy without further anti-cancer treatment.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
59
Issue
3-4
Start Page
280
End Page
283
Sort Key
280
Published Date
2012-08
FullText File
language
eng
TextVersion
Publisher