number of access : ?
number of downloads : ?
ID 106141
Title Alternative
FDG-PET/CTでの浸潤性膵管癌以外の膵腫瘍の悪性病変の検出能における視覚評価と標準摂取率での評価の比較検討
Author
Terazawa, Kaori The University of Tokushima
Nose, Hayato The University of Tokushima
Kubo, Michiko The University of Tokushima
Matsuzaki, Kenji The University of Tokushima KAKEN Search Researchers
Keywords
FDG
PET/CT
pancreatic lesion
Content Type
Thesis or Dissertation
Description
Introduction The utility of FDG PET/CT for the detection and evaluation of invasive ductal carcinoma has been widely reported, but a few studies have assessed the utility of FDG PET/CT to detect malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Purpose To compare the diagnostic performance of visual estimation with the semi-quantitative scores of FDG PET/CT for detecting malignancy in a variety of pancreatic lesions other than invasive ductal carcinoma. Material and Methods Images of pathologically proven pancreatic lesions from 32 patients were retrospectively evaluated : 14 benign lesions, 7 borderline (low malignant) lesions, and 11 malignant lesions. The average scores from visual estimation by the two observers were compared to two semi-quantiative analyses of FDG uptake in the lesions, namely the maximum standardized uptake value (SUVmax) and mean standardized uptake value (SUVmean). Results Visual analysis value, SUVmax and SUVmean were 0.33±0.21, 1.8±0.7 and 1.5±0.7 for the benign lesions, 0.70±0.28, 5.0±2.6 and 3.1±1.7 for the borderline lesions, and 0.73±0.18, 4.7±2.5 and 3.2±1.6 for the malignant lesions, respectively. Receiver operating characteristic analysis revealed the areas under the curves for detecting non-benign (malignant or borderline) lesions through visual analysis, SUVmax, and SUVmean were 0.914, 0.954, and 0.875, respectively. Conclusion For a variety of pancreatic lesions other than invasive ductal carcinoma, visual analysis and semi-quantitative analyses all showed strong diagnostic performance. However, semi-quantitative analysis with SUVmax proved to be the most effective method for detecting non-benign pancreatic lesions.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA12022913
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
61
Issue
1-2
Start Page
171
End Page
179
Sort Key
171
Published Date
2014-02
Remark
内容要旨・審査要旨・論文本文の公開:
内容要旨・審査要旨 : LID201405131012.pdf
論文本文 : k2748_fulltext.pdf
本論文は,著者Yoichi Otomiの学位論文として提出され,学位審査・授与の対象となっている。
著者の申請により要約(2014-07-24公開)に替えて論文全文を公開(2019-12-19)
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第2748号
Diploma Number
甲医第1209号
Granted Date
2014-03-24
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
University Hospital
Medical Sciences