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ID 106142
Title Alternative
軟部病変におけるF-18 FDG PET/CTと病理所見との相関関係
FDG-PET/CT findings of soft tissue lesoions
Author
Nose, Hayato The University of Tokushima
Terazawa, Kaori The University of Tokushima
Keywords
F-18 FDG PET
soft tissue tumor
myxoid tumor
neurogenic tumor
liposarcoma
Content Type
Thesis or Dissertation
Description
Objective : To evaluate the correlations between F-18 FDG uptake imaged with PET/CT and pathological findings in soft tissue lesions. Methods : Fifty-four soft tissue lesions in 47 patients were evaluated. The correlations between the degree of FDG uptake, pathological type and grade, and MRI signal intensity and/or enhancement pattern were evaluated. Tumor FDG uptake was quantified by the maximum standardized uptake value (SUVmax). Results : Thirty-one lesions were malignant and twenty-three lesions were benign. The difference between SUVmax in the malignant and benign groups was statistically significant (p<0.001). Malignant myxoid lesions and well differentiated liposarcoma showed low FDG uptake. Benign neurogenic lesions showed low FDG uptake while malignant neurogenic tumors showed high FDG uptake, and the difference between SUVmax in the benign and malignant lesions was statistically significant (p<0.001). In a neurofibromatosis type-1 patient who had multiple neurogenic tumors, FDG-PET/CT could distinguish malignant peripheral nerve sheath tumors from other benign lesions with similar MRI findings. Conclusions : FDG-PET/CT is useful for differentiating malignant from benign soft tissue lesions, but malignant soft tissue lesions may show various patterns on FDG-PET, and MRI may be helpful for a differential diagnosis.
Journal Title
The Journal of Medical Investigation
ISSN
13496867
13431420
NCID
AA12022913
AA11166929
Publisher
Tokushima University Faculty of Medicine
Volume
60
Issue
3-4
Start Page
184
End Page
190
Sort Key
184
Published Date
2013-08
Remark
内容要旨・審査要旨・論文本文の公開
内容要旨・審査要旨 : LID201405131013.pdf
論文本文 : k2749_fulltext.pdf
本論文は,著者Hayato Noseの学位論文として提出され,学位審査・授与の対象となっている。
著者の申請により要約(2014-05-23公開)に替えて論文全文を公開(2019-12-20)
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
ETD
MEXT report number
甲第2749号
Diploma Number
甲医第1210号
Granted Date
2014-03-24
Degree Name
Doctor of Medical Science
Grantor
Tokushima University
departments
Medical Sciences
University Hospital