ID 109554
Author
Sakai, Toshinori Department of Radiological Sciences, University of California, Irvine|Department of Orthopaedic Surgery, University of California, Irvine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Miyagi, Ryo Department of Radiological Sciences, University of California, Irvine KAKEN Search Researchers
Yamabe, Eiko Department of Radiological Sciences, University of California, Irvine
Fujinaga, Yasunari Department of Radiological Sciences, University of California, Irvine
Bhatia, Nitin N. Department of Orthopaedic Surgery, University of California, Irvine
Yoshioka, Hiroshi Department of Radiological Sciences, University of California, Irvine
Keywords
asymptomatic
lumbar spine
disc herniation
diffusion tensor imaging
diffusion-weighted imaging
Content Type
Journal Article
Description
Diffusion-weighted imaging (DWI) and diffusion tensor imaging (DTI) were performed
on a healthy 31-year-old man with asymptomatic lumbar disc herniation. Although
the left S1 nerve root was obviously entrapped by a herniated mass, neither DWI nor DTI showed any significant findings for the nerve root. Decreased apparent diffusion coefficient (ADC) values and increased fractional anisotropy (FA) values were found. These results are contrary to those in previously published studies of symptomatic patients, in which a combination of increased ADC and decreased FA seem to have a relationship with nerve injury and subsequent symptoms, such as leg pain or palsy. Our results seen in an asymptomatic subject suggest that the compressed nerve with no injury, such as edema, demyelination, or persistent axonal injury, may be indicated by a combination of decreased ADC and increased FA. ADC and FA could therefore be potential tools to elucidate the pathomechanism of radiculopathy.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
61
Issue
1-2
Start Page
197
End Page
203
Sort Key
197
Published Date
2014-02
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences
University Hospital