ID 109588
Author
Saito, Ken Department of Chronomedicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Takeda, Shiho School of Health Sciences, the University of Tokushima
Saito, Yuko Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School
Kawamura, Mami School of Health Sciences, the University of Tokushima
Yoshikawa, Yoko Department of Cardiology, Sekishinkan Hospital
Yano, Hayato Department of Cardiology, Sekishinkan Hospital
Sata, Masataka Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
Paroxysmal AV block
Ambulatory electrocardiography
Circadian rhythm
Syncope
Right bundle branch block
Content Type
Journal Article
Description
The goal of this study was to investigate the electrocardiographic and chronobiological features of paroxysmal atrioventricular (AV) block (PAVB) using data from ambulatory electrocardiography (AECG). The study population consisted of five men and six women aged from 47 to 82 years of age. Main presenting symptoms were pre-syncope in five patients (45.5%) and syncope in three patients (27.3%). Organic cardiovascular diseases were seen in eight patients (72.7%), and AV conduction disturbances were seen in six patients (54.5%), such as right bundle branch block, first to second degree AV block on standard 12-lead electrocardiography. Incidence of PAVB events were 1-329 (37.9±98.0) episodes/patient/day, and the maximum pause during Holter recordings was 3.3-12.4 (6.39±3.09) seconds. This maximum pause caused by intrinsic AV block was longer than that of vagally mediated AV block (8.4±3.2 sec vs 4.7±1.0 sec, p<0.05). In chronobiological analysis, episodes of PAVB exhibited a circadian rhythm characterized by a peak between 2 : 00 am and 4 : 00 am and a trough between 0 : 00 pm and 2 : 00 pm. AECG is a useful tool to detect the maximum pause occurring during sleep and provides critical data necessary to prevent the sudden cardiac death caused by PAVB.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
61
Issue
3-4
Start Page
380
End Page
387
Sort Key
380
Published Date
2014-08
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences