ID 109616
Title Transcription
セイタイ シリョウヨウ カイリョウガタ NMR プローブ ノ サクセイ ト ヒョウカ
Title Alternative
Re-design and evaluation of the NMR probes for living organs and tissues
Author
Kitamura, Mitsuo Department of Physiology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory
Hayano, Takashi Otsu Municipal Hospital
Yoshizaki, Kazuo Department of Physiology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
nmr probe
diffusion
Na
muscle
Content Type
Journal Article
Description
We have constructed NMR signal detectors (probes) to measure the NMR spectra of living organs and tissues kept under physiological conditions. The probes consisted of non-magnetic aluminum alloy cylinder to support the detection coil made of cupper, mounted on a Teflon plate with acrylics plates and rods, however, the recovery time to the static magnetic field after turning off of the pulsed gradient field was more than 10 times longer than that of the micro-MRI probe available commercially.
The re-design of our probes, such as acrylics cylinder to support the coil, together with readjustment of the eddy current compensation circuit, provided us the recovery time to the static field less than 1 msec, making it possible to measure the diffusion coefficient of Na+ ion using the pulsed field gradient spin echo method. The diffusion coefficient of Na+ ion in skeletal muscle isolated from bullfrog was 0.6 time larger than that in Ringer’s solution, suggesting a high viscosity in the skeletal muscle.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
69
Issue
1-2
Start Page
67
End Page
72
Sort Key
67
Published Date
2013-04-25
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
Technical Support Department
Medical Sciences