ID 109636
Title Transcription
ニンシン オ ケイキ ニ ジョウミャク ケッセンショウ オ ハッショウシ センテンセイ アンチトロンビンIII ケッソンショウ ト シンダン サレタ イチレイ
Title Alternative
A case of venous thrombosis due to congenital antithrombin III deficiency triggered by pregnancy
Author
Takagi, Eri Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Ota, Rie Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Niki, Toshiyuki Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Kadota, Muneyuki Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Kawabata, Yutaka Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Hara, Tomoya Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Takashima, Akira Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Bando, Mika Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Bando, Sachiko Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Matsuura, Tomomi Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Ise, Takayuki Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Hocchi, Jyunko Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Ueda, Yuka Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Yamaguchi, Kouji Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Yagi, Shuusuke Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Iwase, Takashi Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school KAKEN Search Researchers
Taketani, Yoshio Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school KAKEN Search Researchers
Tomita, Noriko Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school
Yamada, Hiroyuki Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Soegi, Takeshi Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Wakatsuki, Tetsuzo Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Sata, Masataka Department of Cardiovascular Medicine, Institute of Health Biosciences, the University of Tokushima Graduated school Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Nakayama, Souichiro Department of Obstetrics and Gynecology, Tokushima University Hospital
Maeda, Kazuhisa Department of Obstetrics and Gynecology, Tokushima University Hospital KAKEN Search Researchers
Irahara, Minoru Department of Obstetrics and Gynecology, Tokushima University Hospital Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
antithrombin III deficiency
thrombophilia
venous thrombosis
pregnancy
Content Type
Journal Article
Description
Congenital antithrombin III (AT III) deficiency is an inherited autosomal dominant disorder. Patients often suffer from recurrent venous thromboses that are triggered by several occasions (operation, gestation, trauma, oral contraceptive drug etc.). Moreover, 60% of them are said to be associated with pulmonary embolism.
The patient of this report is 27-year-old pregnant woman in the first trimester. She felt pain in the back of her head and left auricle and presented with dyslexia and aphasia in late of March, 20XX. Getting CT brain scan, MRI brain scan, and blood sampling at the nearby hospital, she was suspected of having thrombosis of left sigmoid and transverse sinus due to AT III deficiency. Because she wanted to give birth to her first child without termination, she was referred to our hospital. We used heparin as the anticoagulant therapy because warfarin had the risk of teratogenesis. But in condition of low serum level of AT III activity, it didn’t work effectively. So we also did frequent complement of AT III. Strict anticoagulant therapy resulted in better outcome for both the patient and her baby without fatal venous thromboses or fetal complications.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
69
Issue
3-4
Start Page
179
End Page
186
Sort Key
179
Published Date
2013-08-25
Remark
著者英表記誤表記あり(誤)Kazutoshi Maeda→(正)Kazuhisa Maeda
FullText File
language
jpn
TextVersion
Publisher
departments
University Hospital
Medical Sciences