ID 109841
Title Transcription
MRI ニ テキゴウ スル イリョウヨウ キンゴウキン ノ カイハツ
Title Alternative
Research & Development of MRI Compatible Au Based Alloys for Biomedical Applications
Author
Hamada, Kenichi Department of Biomaterials and Bioengineering, Institute of Health Bioscience, University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
MRI
金属アーチファクト
磁化率
反磁性
Content Type
Journal Article
Description
Metal-artifact due to volume-magnetic-susceptibility (χ) mismatch between alloy and human-tissue is one of the serious magnetic-resonance-imaging (MRI) artifacts. Alloys of susceptibility close to that of human-tissue (approximately -9 ppm) are thus required for MRI-artifact-free metal-biomedical-devices. Au-28 mass%Pt alloy is a candidate because of its χ and high corrosion resistance. However, the mechanical properties are insufficient for various types of biomedical-device. The authors found that Nb addition could improve the mechanical properties and simultaneously keep the alloy MRI-artifact-free. The authors produced an Au-8Nb-5Pt alloy wire and found that the χ value for this wire increased because of contamination during the production process. To adjust χ, the Nb content in the alloy was optimized and an Au-7Nb-5Pt alloy wire was produced. The χ value of this wire was confirmed to be close to -9 ppm. The Au-7Nb-5Pt alloy wire demonstrates higher mechanical properties than those of Au-28Pt alloy wire, and good formability. Recently, the authors are successfully producing several kinds of experimental vascular devices, such as coils for cerebral aneurysm embolization, cerebral aneurysm clips, and vascular stents. The next step of the current development is to evaluate the mechanical properties of these experimental devices, and to optimize the device designs for clinical usage.
Journal Title
四国歯学会雑誌
ISSN
09146091
NCID
AN10050046
Publisher
四国歯学会
Volume
26
Issue
2
Start Page
29
End Page
34
Sort Key
29
Published Date
2014-02-14
FullText File
language
jpn
TextVersion
Publisher
departments
Oral Sciences