ID 109899
Title Transcription
トクシマ ダイガク ビョウイン ノウソッチュウ センター デノ ナイケイドウミャク キュウセイ ヘイソク ニ タイスル チリョウ センリャク
Title Alternative
Treatment strategy for acute ischemic stroke with internal carotid artery occlusion in the stroke care unit of Tokushima University Hospital
Author
Inoko, Miki The Post-graduate Education Center, Tokushima University Hospital|Department of Stroke Care Unit, Tokushima University Hospital
kuwayama, Kazuyuki Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Nishi, Kyoko The Post-graduate Education Center, Tokushima University Hospital|Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Yamaguchi, Tadashi Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Satomi, Jyunichiro Department of Stroke Care Unit, Tokushima University Hospital|Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN Search Researchers
Yamamoto, Nobuaki Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School
Kaji, Ryuji Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Nagahiro, Shinji Department of Stroke Care Unit, Tokushima University Hospital|Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
ICA occlusion
intra-arterial endovascular therapy
recombinant tissue-type plasminogen activator (rt-PA)
Content Type
Journal Article
Description
Objective : Strokes related to acute internal carotid artery (ICA) occlusion are associated with extremely poor prognosis. Recently, some studies have reported that the prognosis has been getting better by treating with intra-arterial endovascular therapy. We sought to evaluate clinical outcomes in patients with acute ischemic stroke attributable to ICA occlusion treated with intraarterial endovascular therapy or otherwise.
Methods : We reviewed 44 patients who underwent treatment with intra-arterial endovascular therapy or otherwise in our stroke care unit (SCU) from January, 2011 to May, 2014. We compared the prognosis of patients in the 2 treatment groups (endovascular group, n=23 vs nonendovascular group, n=21).
Results : The rate of good prognosis (modified Rankin Score of ≦2) was significantly higher in the endovascular group than non-endovascular group (17.4% vs0%,p=0.045). The rate of patients who had extreme improvements of National Institutes of Health Stroke Scale (NIHSS) ≧8 was higher in the endovascular group than non-endovascular group (30.4% vs14.3%). Concerning the improvement of NIHSS ≧8, recombinant tissue-type plasminogen activator (rt-PA) or the left side ICA occlusion were associated significantly (p=0.019, p=0.042, respectively). Although the hypothesis that endovascular therapy could contribute to extreme improvements of NIHSS wasn’t proved (p=0.202), there was one case that NIHSS was dramatically improved from 22 to 0 by endovascular therapy.
Conclusions : Intra-arterial endovascular therapy of ICA occlusion might result in improved clinical outcomes for indicated cases.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
70
Issue
5-6
Start Page
167
End Page
172
Sort Key
167
Published Date
2014-12-25
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
University Hospital
Medical Sciences