ID 110186
Title Transcription
ガイライ ケンシン ニオケル メタボリック シンドローム ト HbA1c 5.4~5.7% ノ リンショウテキ イギ : トクニ hs-CRP ト インスリン テイコウセイ ニツイテ
Title Alternative
Clinical significance of aged-group in mass examination on metabolic syndrome and HbA1c 5.4~5.7%
Author
Mitani, Hiroaki Mitani Clinic
Keywords
Metabolic syndrome
insulin resistance
hs-CRP
Content Type
Journal Article
Description
To estimate of frequency of metabolic syndrome(MetS)in relatively aged mass examination(n=367), 75gOGTT were particularly studied 76 out of 96 subjects to have been indicated levels of5.4~5.7%, moreover were compared to other clinical parameters. Frequency of MetS to be consideredmore than BS 110mg/dl were 4.5%, that’s of above HbA1c 5.5% were 31.5% in general mass.Because of OGTT there were recognized IGT about 1/2 of HbA1c 5.4%, 3/4 of 5.5~5.7% grouprespectively, that’s more was significantly increased HOMA-IR and decreased % FFA30 in HbA1c5.5~5.7%. The clinical characteristics of aged-MetS were obesity, low HDL-C/high TG, low adiponectin(Adipo.)/high Leptin, high IRI/FFA, elevated HOMA-IR, but not BS of OGTT. Thegroup of over HOMA-IR 1.7 were indicated waist obesity, low Adipo./high Lepin, high IRI/FFAand hypertension, and following relatively high hs-CRP(500ng/ml<)group were recognized lowHDL-C, high BS after OGTT, elevated IRI(120min), FFA and high HOMA-IR but not the frequencyof MetS and hypertension. In comparison with both parameters and clinical examinationsthere were significant relationship on Leptin, F-IRI and FFA.From these results it was thought that participate the route of FFA-Macrophage and insulinresistance.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
63
Issue
3-4
Start Page
127
End Page
133
Sort Key
127
Published Date
2007-08-25
FullText File
language
jpn
TextVersion
Publisher