ID 110201
Title Transcription
ジヘイショウ ノ シンダン チリョウ サイゼンセン
Title Alternative
Advances in neurology of autism
Author
Mori, Kenji Department of Pediatrics, Institute of Health Bioscience, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Fujii, Emiko Department of Pediatrics, Institute of Health Bioscience, The University of Tokushima Graduate School
Miyazaki, Masahito Department of Pediatrics, Institute of Health Bioscience, The University of Tokushima Graduate School
Kagami, Shoji Department of Pediatrics, Institute of Health Bioscience, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
autism
amygdale
mirror neuron system
Content Type
Journal Article
Description
In this paper we review the pathophysiology of autism.1)The amygdala theory of autismThe network of neural regions that comprise the social brain includes the amygdala. There isa reduction in volume of amygdala in children with autism. The concentration of N-acetylaspartateis also decreased in amygdala of autistic brain. The amygdala is therefore proposed to be one ofseveral neural regions that are abnormal in autism.2)Mirror neuron dysfunction in autismChildren with autism underwent fMRI while imitating and observing emotional expressions.They showed no mirror neuron activity in the inferior frontal gyrus(pars opercularis). Notably,activity in this area was inversely related to symptom severity in the social domain, suggestingthat a dysfunctional mirror neuron system may underlie the social deficits observed in autism.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
63
Issue
5-6
Start Page
187
End Page
193
Sort Key
187
Published Date
2007-12-20
FullText File
language
jpn
TextVersion
Publisher
departments
Medical Sciences