ID 110284
Title Transcription
ミギテユビ ニ キュウソクニ エソセイ ビョウヘン オ ショウジタ コウリンシシツ コウタイ ショウコウグン ノ 1レイ
Title Alternative
A case of antiphospholipid syndrome with rapidly progressive necrotic skin lesions on the right fingers
Author
Niki, Mariko The Post-graduate Education Center, Tokushima University Hospital Tokushima University Educator and Researcher Directory
Inoue, Natsuko Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Fukumoto, Daisuke Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Yamamoto, Tadamasa Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Ansai, Sinichi Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School
Kubo, Yoshiaki Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Arase, Seiji Department of Dermatology, Institute of Health Biosciences, the Universitiy of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
rapidly progressive necrotic skin lesions
mixed connective tissue disease
lupus anticoagulant
antiphospholipid syndrome
Content Type
Journal Article
Description
A 77‐year‐old female was referred to our clinic in July 4,2008 with a week history of rapidly progressive necrotic skin lesions on her right fingers. She had been under treatments of mixed connective tissue disease(MCTD)since 1991. Laboratory findings revealed prolongation of activated partial thromboplastin time(aPTT)and the presence of lupus anticoagulant. We diagnosed this case as MCTD followed by antiphospholipid syndrome(APS). After the treatment of Prostaglangin E1and Sarpogrelate hydrochloride, low dose of oral aspirin was started. Necrotic lesions of her fingers improved gradually, and she was discharged in September21. APS should be considered when we see rapidly progressive necrotic skin lesions on patients with collagen deseases.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
65
Issue
3-4
Start Page
98
End Page
102
Sort Key
98
Published Date
2009-08-25
FullText File
language
jpn
TextVersion
Publisher
departments
Medical Sciences
University Hospital