ID 110300
Title Transcription
サンカ マグネシウム ノ ケッチュウ Mg ノウド オヨビ ジンキノウ ニ オヨボス エイキョウ ニツイテ
Title Alternative
Clinical study on serum Mg concentration and kidney functions of outpatients to be treated with magnesium oxide
Author
Mitani, Hiroaki Mitani Clinic
Keywords
magnesium oxide
serum Mg concentration
kidney functions
Content Type
Journal Article
Description
Last year it was reported that the side effects by magnesium oxide(MgO)were noticed on chronic kidney disease(CKD), and then to estimate serum Mg concentration and kidney functions in outpatients, that is group(n=71)to be treated with MgO(1.68g/day), untreated control group (n=129)and group(n=24)of Warfarin treatment were examined. Moreover, out of27treated subjects serum levels of clinical parameters, such as serum uric acid, BUN, creatinine, Ca, P, Mg (mg/dl)and GFR(ml/min/1.732)were studied before and after treatment. Serum Mg concentration of treated, untreated and Warfarin group were 2.51±0.29*,2.38±0.22and2.24±0.24** mg/dl respectively, the former* was higher and the latter** was lowered. To compare with GFR ≧ 60and <60serum magnesium was only elevated in the latter with CKD to be treated with MgO. What’ s more discontinued group were gradually lowered serum Mg(2.63±0.21to2.47±0.14), Ca and P in27treated group. From these results it was partly suspected that MgO was affected to serum electrolyte in outpatients, therefore some patients with CKD were a little observed clinical examinations and symptoms, but these patients with GFR ≧60were not so anxious concerned.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
65
Issue
5-6
Start Page
181
End Page
186
Sort Key
181
Published Date
2009-12-20
FullText File
language
jpn
TextVersion
Publisher