ID 110309
Title Transcription
エイヨウ ト メンエキ キノウ : ヒヒッス エイヨウソ テイエイヨウ ジョウタイ カエイヨウ ジョウタイ ト メンエキ
Title Alternative
Nutrition and immunity
Author
Sakai, Tohru Department of Public Health and Applied Nutrition, Institute of Health Bioscience, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Nakamoto, Mariko Department of Public Health and Applied Nutrition, Institute of Health Bioscience, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Shuto, Emi Department of Public Health and Applied Nutrition, Institute of Health Bioscience, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Hosaka, Toshio Department of Public Health and Applied Nutrition, Institute of Health Bioscience, the University of Tokushima Graduate School
Keywords
soy isoflavone
genistein
equol
obesity
T cell
Content Type
Journal Article
Description
It is known that nutritional state crucially affects immune function. In recent years, the contributionof the diet to the optimal working of the immune system has become wildly appreciatedand the influence of different dietary components on specific aspects of immune function has beenextensively studied. Soy isoflavone genistein suppresses antigen-specific immune response inBALB/c mice and suppresses development of atopic-like dermatitis in NC/Nga mice. In other soyisoflavone equol enhances antigen-specific IgE production via IL-13-mediated pathway. Further,equol exacerbates colitis of dextran sulfate sodium-treated mice. Therefore, immune stimulatoryeffects are strikingly different among soy isoflavones. In this reviews, in addition of the isoflavone,we overview the effects of dietary nucleic acid and protein-deficiency on antigen-specific immuneresponses. Furthermore, we present hot topics researches in the field of obesity and T cellfunction.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
66
Issue
1-2
Start Page
19
End Page
26
Sort Key
19
Published Date
2010-04-25
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
Medical Sciences