ID 110328
Title Transcription
メンタル ヘルス オ ササエル エイヨウ カガク : ショクヒン セイブン ノ コウウツヨウ カッセイ ヒョウカ
Title Alternative
Nutritional science and mental health : antidepressant activity of food ingredients and its evaluation
Author
Terao, Junji Department of Food Science, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
stress control
antdepressant activity
plant polyphenols
monoamine oxidase-A
HPA axis
Content Type
Journal Article
Description
Nowadays anti-stress effect of food ingredients attracts much attention from the standpoint of maintenance of mental health. Nevertheless, definitive evidence on the effect is very few in human studies. The University of Tokushima proceeded the21st -Century COE Program,“Human Nutrition Science on Stress Control”, from 2004 to 2008. In this program, we carried out the screening and evaluation of antidepressant-like effect of plant polyphenols. It is suggested that plant polyphenols are able to suppress brain mitochondrial monoamine oixidase-A(MAO-A)activity which is responsible for the serotonin metabolism in synapses. In addition, intake of quercetin, a representative plant polyphenol, seems to affect hypothalamus-pituitary gland-adrenal cortex axis(HPA axis)leading to the suppression of plasma cortisol. It is therefore likely that plant polyphenols act as anti-stress ingredients from foods to contribute metal health, although more studies including human trials are obviously required.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
66
Issue
5-6
Start Page
123
End Page
126
Sort Key
123
Published Date
2010-12-20
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
Medical Sciences