ID 110375
Title Transcription
ヒマン トウニョウビョウ コクフク オ モクテキ トシタ シボウ サイボウ ケンキュウ ノ ジッセン ト エイヨウガク ケンキュウ エノ テンカイ
Title Alternative
The research of adipocyte biology for the survive from obesity and diabetes and its development into nutritional intervention
Author
Sakaue, Hiroshi Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kuroda, Masashi Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima University Educator and Researcher Directory
Sebe, Mayu Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School
Tsutsumi, Rie Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
obesity
Diabetes
Adipocyte
Hyperplasia and hypertrophy
Content Type
Journal Article
Description
White adipose tissue(WAT)is the main storage site for excess energy as triacylglycerides within specialized lipid-laden mature adipocytes. The expansion of WAT during the development of obesity can occur through increases in cell number(adipocyte hyperplasia)and in cell size(adipocyte hypertrophy). Adipocytes are derived from preadipocytes which can proliferate throughout life to increase WAT mass. In addition, adipocyte cell death observed within pathologically expanding adipose tissue is also one of the important factors that contribute to the pathophysiological consequences of obesity. The objective of this review is to discuss the precise contribution of adipocyte life cycle to the pathogenesis of obesity and obesity-related disease and to indicate substantial progress in our lab concerning our knowledge of bioactive components in functional foods and their links to obesity.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
72
Issue
1-2
Start Page
19
End Page
24
Sort Key
19
Published Date
2016-04-25
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
Medical Sciences