ID 110387
Title Transcription
トクシマ ダイガク ビョウイン ノウソッチュウ センター ニ ハンソウ サレタ rt-PA ジョウチュウ リョウホウ ノ Drip and Ship ショウレイ ニオケル ケントウ
Title Alternative
“Drip and Ship”Cases of Intravenous rt-PA Therapy Transported to Stroke Care Unit
Author
Nunomura, Toshiyuki The Post-graduate Education Center, Tokushima University Hospital|Department of Stroke Care Unit, Tokushima University Hospital,
Kanematu, Yasuhisa Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Yamakami, Kei The Post-graduate Education Center, Tokushima University Hospital|Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School
Nishi, Kyoko The Post-graduate Education Center, Tokushima University Hospital|Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Yamamoto, Yuki Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School
Yamamoto, Nobuaki Department of Neurology, Institute of Health Biosciences, the University of Tokushima Graduate School
Azumi, Mai Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Nishiyama, Toru Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Kagusa, Hirosi Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Yamaguchi, Izumi Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Yoshioka, Syotarou Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School
Satomi, Junichiro Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School KAKEN Search Researchers
Nagahiro, Shinji Department of Neurosurgery, Institute of Health Biosciences, the University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
Drip and Ship
recombinant tissue-type plasminogen activator
endovascular therapy
Content Type
Journal Article
Description
Recently,“Drip and Ship”treatment conducted in collaboration of a hospital in remote area and an institution capable of emergency stroke treatment under guidance by a stroke specialist has been reported to be effective. “Drip and Ship” treatment refers to initiating intravenous recombinant tissue-type plasminogen activator(rt-PA)infusion at a remote hospital(Drip)and then transporting patients to an institution capable of multimodality management and endovascular treatment of stroke(Ship). We report here a case analysis and examinations on treatment methods, prognosis, and some other parameters in 16 patients who were transported to the Stroke Care Unit(SCU)of the Tokushima University Hospital while undergoing“Drip and Ship”treatment between June 2013 and November 2015. Occluded vessels were recanalized by rt-PA administration in 5/12patients (42%). For 6 cases in which recanalization was not achieved with rt-PA, endovascular treatment was performed, and recanalization was obtained in 3 patients(50%). There was a marked improvement(8.4points on average)in NIHSS at the time of discharge compared to that before rt-PA administration. A representative case showed a 26‐point improvement in NIHSS at the time of discharge compared to the pretreatment value. The advantage of“Drip and Ship”treatment is two-fold : It allows for rt-PA treatment of acute ischemic stroke patients at remote-area institutions incapable of multimodality stroke management, and also makes it possible to add endovascular treatment for rt-PA-irresponsive cases in which recanalization of occluded vessels could not be achieved with rt-PA therapy. The results suggest that the“Drip and Ship”treatment is a safe and effective means to eliminate regional disparities in intravenous rt-PA therapy and can make more contributions to the collaborative stroke care in the Tokushima prefecture in the future.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
72
Issue
3-4
Start Page
107
End Page
112
Sort Key
107
Published Date
2016-08-25
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
University Hospital
Medical Sciences