ID 110416
Title Transcription
ゲンパツセイ コウジョウセンガン ノ ネンレイ ニヨル リンショウ ビョウリガクテキ トクチョウ オヨビ ヨゴ ノ ヒカク ケントウ
Title Alternative
The impact of age on clinicopathologic features and prognosis of primary thyroid cancer
Author
Kontani, Keiichi Department of Thoracic, Breast and Endocrine Surgery, Kagawa University Faculty of Medicine
Morishita, Atsushi Department of Surgery, Takamatsu Red Cross Hospital
Kubo, Takako Department of Surgery, Takamatsu Red Cross Hospital
Hashimoto, Shin-ichiro Department of Thoracic, Breast and Endocrine Surgery, Kagawa University Faculty of Medicine
Murazawa, Chisa Department of Thoracic, Breast and Endocrine Surgery, Kagawa University Faculty of Medicine
Norimura, Shoko Department of Surgery, Takamatsu Red Cross Hospital
Hashimoto, Nozomi Department of Thoracic, Breast and Endocrine Surgery, Kagawa University Faculty of Medicine
Kenzaki, Koichiro Department of Surgery, Takamatsu Red Cross Hospital
Tamaki, Masafumi Department of Surgery, Takamatsu Red Cross Hospital
Miura, Kazumasa Department of Surgery, Takamatsu Red Cross Hospital
Yokomise, Hiroyasu Department of Thoracic, Breast and Endocrine Surgery, Kagawa University Faculty of Medicine
Keywords
primary thyroid cancer
age
prognosis
Content Type
Journal Article
Description
Two-hundred thirty-six patients with primary thyroid cancer who received operation were divided into two groups by age, i.e.,59patients of age <45years(Early adulthood, EA)and177 patients of age≧45years(advanced age, AA). Clinicopathologic factors and disease-free survival (DFS)were compared between the two groups. There was no difference in clinicopathologic factors except for higher proportion of patients with poorly differentiated adenocarcinoma in the AA patients than in the EA patients(6.7% vs. 0%, p=0.041). DFS was significantly longer in the AA patients than in the EA patients(disease-free rates at10years after operation,94.8% vs. 72.5%, p=0.0031). Overall survival was not different between the two groups. The EA patients who showed shorten DFS were divided into two groups,17 patients of age <30 years (juvenile and young adult, JYA)and 42 patients of age ≧30 years, and DFS of each group was compared with that of the AA patients. Although disease-free survival rates at 10 years of the JYA patients were not different(92.6% vs.94.8%, p=0.125), those of patients of age ≧30years were significantly lower than those of the AA patients(70.0% vs. 94.8%, p=0.0021). These findings suggest that patients with primary thyroid cancer who are ≧30 years old in the young adulthood should be observed carefully after operation for early detection of relapse.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
73
Issue
1-2
Start Page
59
End Page
64
Sort Key
59
Published Date
2017-04-25
FullText File
language
jpn
TextVersion
Publisher