ID 110487
Title Transcription
コウレイシャ ノ ヒフ シュヨウ
Title Alternative
Skin tumors in aged patients
Author
Kubo, Yoshiaki Department of Dermatology, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Urano, Yoshio Division of Dermatology, Tokushima Red Cross Hospital
Minami, Mitsuyoshi Department of Dermatology, The University of Tokushima School of Medicine
Arase, Seiji Department of Dermatology, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
skin tumors
ultra-violet (UV) radiation
mutagenesis
ozone layer
sunscreen
Content Type
Journal Article
Description
Skin tumors in aged patients consist of benign tumors, precancerous lesions or carcinomas in situ, and skin cancers. We reviewed the clinical characteristic and treatment for each of them, and the molecular pathogenesis and protection for skin cancers. Exposure to ultra-violet (UV) radiation is the most common cause of skin cancers. In particular, UV-B radiation is mainly involved in the mutagenesis in the skin by two major photoproducts of a cyclobutane pyrimidine dimer and a (6-4) photoproduct. Recently, the ozone layer of the earth has been destroyed, and the increase in UV-B radiation on the earth surface can be expected in the next years. Therefore, we should add special attention to patients with skin cancers that are predicted to increase in number, and UV protection by sunscreens from childhood should be essential for the prevention against skin cancers in the 21st century.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
57
Issue
3
Start Page
53
End Page
57
Sort Key
53
Published Date
2001-06-25
FullText File
language
jpn
TextVersion
Publisher
departments
Medical Sciences