ID 110538
Title Transcription
アタラシイ リウマチ チリョウホウ
Title Alternative
Clinical efficacy of anti-cytokine therapy in rheumatoid arthritis
Author
Tani, Kenji Department of Internal Medicine and Molecular Therapeutics, Course of Medical Oncology, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Sone, Saburo Department of Internal Medicine and Molecular Therapeutics, Course of Medical Oncology, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
rheumatoid arthritis
tumor necrosis factor-α
etanercept
infliximab
Content Type
Journal Article
Description
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by the progressive destruction of joints. Cytokines such as tumor necrosis factor (TNF)-α, interleukin (IL)-1, IL-6 and IL-8 have a critical role in the pathogenesis of RA. Recently, etanercept and infliximab, which block the action of TNF-α, can reduce the disease activity of RA. They act more rapidly to decrease symptoms and slow joint damage in patients with early active RA than methotrexate. This article describes recent studies on anti-cytokine therapy in RA.
Journal Title
四国医学雑誌
ISSN
00373699
NCID
AN00102041
Publisher
徳島医学会
Volume
58
Issue
3
Start Page
122
End Page
126
Sort Key
122
Published Date
2002-06-15
EDB ID
FullText File
language
jpn
TextVersion
Publisher
departments
University Hospital
Medical Sciences