ID 110632
Author
Sun, Xue-Zhi Environmental and Toxicological Sciences Research Group, National Institute of Radiological Sciences
Takahashi, Sentaro Environmental and Toxicological Sciences Research Group, National Institute of Radiological Sciences
Cui, Chun Department of Anatomy, The University of Tokushima School of Medicine
Inoue, Minoru Shin Nippon Biomedical Laborarories, Ltd
Fukui, Yoshihiro Department of Anatomy, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
GABAergic neuron
calbindin-D28K
calcium-binding protein
immunocytochemistry
primary motor cortex
Content Type
Journal Article
Description
Distribution of calbindin-D28K immunoreactive cells in the primary motor area of the adult rat neocortex was studied in the present experiment. In the primary motor cortex, calbindin-D28K immunoreactivity was found in two populations of cortical neurons. One was composed of neurons heavily labeled with anti-calbindin antibody, which were present in two bands corresponding to cortical layers II-III, and V. The morphological types of these cells were varied they had oval, fusiform or mutiangular somata. The proximal dendrites of the heavily stained cells showed that these cells were non-pyramidal neurons, and they were either bitufted or multipolar cells. The other was a weakly stained population, mainly concentrated in layers II and III, that also contained pyramidal neurons. In addition, one outstanding feature of the neuropil staining deep to layer II was the labeling of the long, vertically oriented bundles of immunoreactive processes. Such a distinct pattern of calbindin-D28K immunoreactive neurons in the primary motor cortex suggests a relatively high density of calcium channels exists in the superficial layers of the rat primary motor cortex.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
49
Issue
1-2
Start Page
35
End Page
39
Sort Key
35
Published Date
2002
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences