ID 110680
Author
Yanagawa, Hiroaki Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Shiraga, Minoru Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Nakamura, Youichi Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Azuma, Masahiko Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Yoneda, Kazuo Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Ogawa, Hirohisa Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Kitamuro, Chikato Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Maeda, Ken-ichi Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Miki, Mari Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Matsumori, Yuka Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Sugita, Akemi Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Hashimoto, Sakiko Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Hara, Chie Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine
Tani, Kenji Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Sone, Saburo Department of Internal Medicine and Molecular Therapeutics, The University of Tokushima School of Medicine Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
bronchial asthma
inhaled corticosteroids
hospitalization
anti-leukotrienes
Content Type
Journal Article
Description
With the recognition that airway inflammation is present even in patients with mild bronchial asthma, therapy with inhaled corticosteroids is now indicated in various stages of patients. In the present article, we retrospectively examined the prescriptions for inhaled corticosteroids and other drugs for the treatment of outpatients with bronchial asthma at Tokushima University Hospital. We also analyzed asthma control in these patients, in terms of the incidence of emergency consultations and hospitalizations due to asthma exacerbations. To analyze the recent trend, the patients observed from 1998 to 2000 (recent years) were included, and for control purpose, those in 1990 and 1991 (earlier years) were also included.
The percentage of patients treated with inhaled corticosteroids remarkably increased in recent years (mean 81.3%) compared to earlier years (mean 23.5%). In contrast, the usage of oral corticosteroids, oral xanthine derivatives, β2-adrenergic receptor agonists and anti-allergic agents tended to decrease in the 10 years period. After the introduction in 1995, considerable patients up to 25% have been treated with anti-leukotrienes. Emergency consultations decreased in recent years (mean 0.18/patient/year) compared to earlier years (mean 0.79/patient/year). Emergency hospitalizations also decreased in recent years (mean 0.043/patient/year) compared to earlier years (mean 0.23/patient/year).In the present study, spread of inhaled corticosteroid therapy and decline in incidence of emergency consultation and hospitalization were simultaneously observed at Tokushima University Hospital, and the former has, at least in part, a contribution to the latter.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
50
Issue
1-2
Start Page
72
End Page
77
Sort Key
72
Published Date
2003
EDB ID
FullText File
language
eng
TextVersion
Publisher
departments
University Hospital
Medical Sciences
Health Service and Counseling Center