ID 110776
Author
Furutani, Kaori Department of Radiology, Institute of Health Biosciences, The University of Tokushima Graduate School
Harada, Masafumi Department of Radiologic Technology, School of Medicine, The University of Tokushima Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Minato, Masako Department of Radiology, Institute of Health Biosciences, The University of Tokushima Graduate School
Morita, Naomi Department of Radiology, Institute of Health Biosciences, The University of Tokushima Graduate School
Nishitani, Hiromu Department of Radiology, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
magnetic resonace imaging
diffusion tensor image
Statistical Parametric Mapping
normal aging
Content Type
Journal Article
Description
Objective :There has been reports on the usefulness of diffusion tensor imaging (DTI) about age-or disease-related degradation. DTI is generally evaluated by the region of interest (ROI) methodology. In this study, we applied a statistical way using Statistical Parametric Mapping (SPM) to assess normal aging by DTI and compared results of these two methods. Methods : Ten young and ten senior normal volunteers were examined. On SPM, tensor images were changed into normalized tensor images. They were compared between the two groups by t-test. Results : In the senior group, fractional anisotropy (FA) values were higher on the basal ganglia, cingulated gyrus and other cortical gray matter, lower in the corona radiata, internal capsule, centrum semiovale and corpus callosum by using SPM. In the ROI method, the results were almost compatible except in the brain periphery. Conclusions : Aging changes on water diffusion anisotropy was clearly shown by SPM method which would be useful to evaluate change of water diffusion anisotropy without operator bias even in clinical setting instead of ROI measurement.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
52
Issue
3-4
Start Page
186
End Page
190
Sort Key
186
Published Date
2005-08
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences