ID 110801
Author
Watanabe, Tomonori Department of Digestive and Cardiovascular Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School
Nomura, Masahiro Faculty of Integrated Art and Sciences, Department of Human and Social Sciences, The University of Tokushima
Nakayasu, Kimiko Faculty of Integrated Art and Sciences, Department of Human and Social Sciences, The University of Tokushima
Kawano, Tomohito Department of Digestive and Cardiovascular Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School
Ito, Susumu Department of Digestive and Cardiovascular Medicine, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory
Nakaya, Yutaka Department of Nutrition and Metabolism, Institute of Health Biosciences, The University of Tokushima Graduate School Tokushima University Educator and Researcher Directory KAKEN Search Researchers
Keywords
thermic effect of food (TEF)
insulin resistance
autonomic nervous activity
heart rate variability
Content Type
Journal Article
Description
Background: The thermic effect of food (TEF) is higher in lean than in obese human subjects. Objective: Relationships between TEF and insulin resistance during meals, from the point of view of autonomic nervous activity, were evaluated. Methods : Autonomic nervous activity was evaluated in 20 young adults using the spectral analysis of heart rate variability from one hour before to two hours after a meal. Heart rate data were analyzed based on low frequency components (LF power, 0.04 - 0.15Hz),high frequency components (HF power, 0.15-0.40 Hz), and LF/HF ratios. Energy expenditure and the TEF were measured 30 min after a meal. Homeostasis model of insulin resistance index (HOMA-IR) was also measured. Results : The LF/HF ratio was significantly increased 30minafter a meal (p<0.05).No correlation between LF power and HF power with TEF was found, but the LF/HF ratio was significantly and positively correlated with TEF(r=+0.56,p<0.05). Moreover, a significant negative correlation was found between the HOMA-IR and TEF (r=-0.601, p<0.05). Conclusions : The findings suggest that a reduction in insulin sensitivity induces a poor response of sympathetic nervous activity in the postprandial phase and a reduction in postprandial energy expenditure.
Journal Title
The journal of medical investigation : JMI
ISSN
13431420
NCID
AA11166929
Volume
53
Issue
1-2
Start Page
153
End Page
158
Sort Key
153
Published Date
2006-02
EDB ID
DOI (Published Version)
URL ( Publisher's Version )
FullText File
language
eng
TextVersion
Publisher
departments
Medical Sciences